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942145-26-8

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  • CarbaMic acid, N-[(1S)-1-(azidoMethyl)-2-[(3R)-tetrahydro-2H-pyran-3-yl]ethyl]-N-Methyl-, 1,1-diMethylethyl ester

    Cas No: 942145-26-8

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942145-26-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 942145-26-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,4,2,1,4 and 5 respectively; the second part has 2 digits, 2 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 942145-26:
(8*9)+(7*4)+(6*2)+(5*1)+(4*4)+(3*5)+(2*2)+(1*6)=158
158 % 10 = 8
So 942145-26-8 is a valid CAS Registry Number.
InChI:InChI=1/C14H26N4O3/c1-14(2,3)21-13(19)18(4)12(9-16-17-15)8-11-6-5-7-20-10-11/h11-12H,5-10H2,1-4H3/t11-,12+/m1/s1

942145-26-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-Methyl-2-propanyl {(2S)-1-azido-3-[(3R)-tetrahydro-2H-pyran-3-y l]-2-propanyl}methylcarbamate

1.2 Other means of identification

Product number -
Other names tert-butyl (S)-1-azido-3-((R)-tetrahydro-2H-pyran-3-yl)propan-2-yl(methyl)carbamate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:942145-26-8 SDS

942145-26-8Downstream Products

942145-26-8Relevant articles and documents

Discovery of VTP-27999, an alkyl amine renin inhibitor with potential for clinical utility

Jia, Lanqi,Simpson, Robert D.,Yuan, Jing,Xu, Zhenrong,Zhao, Wei,Cacatian, Salvacion,Tice, Colin M.,Guo, Joan,Ishchenko, Alexey,Singh, Suresh B.,Wu, Zhongren,McKeever, Brian M.,Bukhtiyarov, Yuri,Johnson, Judith A.,Doe, Christopher P.,Harrison, Richard K.,McGeehan, Gerard M.,Dillard, Lawrence W.,Baldwin, John J.,Claremon, David A.

, p. 747 - 751 (2011/12/01)

Structure guided optimization of a series of nonpeptidic alkyl amine renin inhibitors allowed the rational incorporation of additional polar functionality. Replacement of the cyclohexylmethyl group occupying the S1 pocket with a (R)-(tetrahydropyran-3-yl)

RENIN INHIBITORS

-

, (2009/01/23)

Described are compounds that bind to aspartic proteases to inhibit their activity. They are useful in the treatment or amelioration of diseases associated with aspartic protease activity. Also described are methods of use of the compounds described herein in ameliorating or treating aspartic protease related disorders in a subject in need thereof.

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