943834-86-4

Basic information

• Product Name: [3-(3-chlorophenyl)-1,2-benzisoxazol-5-yl](5-chloro-2-thienyl)methanone
• Synonyms: [3-(3-chlorophenyl)-1,2-benzisoxazol-5-yl](5-chloro-2-thienyl)methanone
• CAS NO: 943834-86-4
• Molecular Weight: 374.247
• Mol File: 943834-86-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: [3-(3-chlorophenyl)-1,2-benzisoxazol-5-yl](5-chloro-2-thienyl)methanone(CAS DataBase Reference)
• NIST Chemistry Reference: [3-(3-chlorophenyl)-1,2-benzisoxazol-5-yl](5-chloro-2-thienyl)methanone(943834-86-4)
• EPA Substance Registry System: [3-(3-chlorophenyl)-1,2-benzisoxazol-5-yl](5-chloro-2-thienyl)methanone(943834-86-4)

Safety Data

• Hazardous Substances Data: 943834-86-4(Hazardous Substances Data)

Upstream product

• 288391-73-1 5-Bromo-3-(3-chloro-phenyl)-benzo[c]isoxazole 
• 7283-96-7 5-Chloro-2-thiophenecarboxaldehyde 
• 943834-85-3 [3-(3-chlorophenyl)-1,2-benzisoxazol-5-yl](5-chloro-2-thienyl)methanol 

Downstream Products

• 406196-65-4 [4-amino-3-(3-chlorobenzoyl)phenyl](5-chloro-2-thienyl)methanone 
• 943834-87-5 7-[chloro(5-chloro-2-thienyl)(1-methyl-1H-imidazol-5-yl)methyl]-5-(3-chlorophenyl)tetrazolo[1,5-a]quinazoline 
• 406196-99-4 ClC₆H₄C₈H₃N₅COHC₄H₂SClC₃H₂N₂CH₃ 
• 406196-70-1 2-chloro-4-(3-chlorophenyl)-α-(5-chloro-2-thienyl)-α-(1-methyl-1H-imidazol-5-yl)quinazoline-6-methanol 
• 406196-69-8 [2-chloro-4-(3-chlorophenyl)-6-quinazolinyl](5-chloro-2-thienyl)methanone 
• 406196-68-7 4-(3-chlorophenyl)-6-[(5-chloro-2-thienyl)carbonyl]-2(1H)-quinazolinone 
• 406196-67-6 2,2,2-trichloro-N-[2-(3-chlorobenzoyl)-4-[(5-chloro-2-thienyl)carbonyl]phenyl]acetamide 

Relevant articles and documents

Impact on farnesyltransferase inhibition of 4-chlorophenyl moiety replacement in the Zarnestra series

Based on the structure of R115777 (tipifarnib, Zarnestra), a series of farnesyltransferase inhibitors have been synthesized by modification of the 2-quinolinone motif and transposition of the 4-chlorophenyl ring to the imidazole or its replacem