944335-22-2

Basic information

• Product Name: (2S)-4-[4-(benzyloxy)phenyl]butane-1,2-diol
• Synonyms: (2S)-4-[4-(benzyloxy)phenyl]butane-1,2-diol
• CAS NO: 944335-22-2
• Molecular Weight: 272.344
• Mol File: 944335-22-2.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: (2S)-4-[4-(benzyloxy)phenyl]butane-1,2-diol(CAS DataBase Reference)
• NIST Chemistry Reference: (2S)-4-[4-(benzyloxy)phenyl]butane-1,2-diol(944335-22-2)
• EPA Substance Registry System: (2S)-4-[4-(benzyloxy)phenyl]butane-1,2-diol(944335-22-2)

Safety Data

• Hazardous Substances Data: 944335-22-2(Hazardous Substances Data)

Upstream product

• 134721-17-8 1-(benzyloxy)-4-(but-3-en-1-yl)benzene 
• 68486-77-1 3-(4-(benzyloxy)phenyl)propanal 
• 6272-45-3 4-benzyloxycinnamic acid 
• 61440-45-7 3-[4-(benzyloxy)phenyl]propan-1-ol 
• 5544-60-5 4-(benzyloxy)benzyl bromide 
• 836-43-1 4-benzyloxybenzyl alcohol 
• 4397-53-9 p-benzyloxybenzaldehyde 
• 123-08-0 4-hydroxy-benzaldehyde 
• 100-39-0 benzyl bromide 
• 1638640-10-4 C₂₃H₂₅NO₃ 
• 69172-21-0 4-(4-Benzyloxyphenyl)butanal 
• 1166181-77-6 methyl 4-[4-(benzyloxy)phenyl]butanoate 
• 243641-03-4 C₁₈H₁₈O₃ 
• 944335-20-0 4-{2-[(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]ethyl}phenol 

Downstream Products

• 944335-23-3 (2S)-4-[4-(benzyloxy)phenyl]-2-hydroxybutyl 4-methyl-1-benzenesulfonate 
• 59092-94-3 (R)-rhododendrol 
• 138948-80-8 (2R)-4-[4-(benzyloxy)phenyl]butan-2-ol 
• 1010127-34-0 (2S)-2-{2-[4-(benzyloxy)phenyl]ethyl}oxirane 
• 767330-04-1 (-)-(3S)-1-[4-(benzyloxy)phenyl]hex-5-en-3-ol 
• 1638640-04-6 ({(3S)-1-[4-(benzyloxy)phenyl]hex-5-en-3-yl}oxy)(tert-butyl)(dimethyl)silane 
• 1638640-11-5 C₂₅H₃₆O₃Si 
• 1258516-47-0 {(1S)-3-[4-(benzyloxy)phenyl]-1-{[(2S)-oxiran-2-yl]methyl}propoxy}(tert-butyl)dimethylsilane 
• 1443256-45-8 (3S,5R)-1-(4-hydroxyphenyl)nonadecane-3,5-diol 

Relevant articles and documents

Catalytic δ-hydroxyalkynone rearrangement in the stereoselective total synthesis of centrolobine, engelheptanoxides A and C and analogues

A catalytic stereoselective total synthesis of centrolobine and engelheptanoxides A and C has been completed via a metal-free catalytic δ-hydroxyalkynone rearrangement to 2,3-dihydro-4H-pyran-4-one and diastereoselective hydrogenation to the all syn-2,4,6-trisubstituted pyran strategy. The onliest required chirality was introduced by Jacobsen kinetic resolution, which further directed the diastereoselective hydrogenation. A first stereoselective synthesis of engelheptanoxide A is also accomplished. The analogues and derivatives of centrolobine and engelheptanoxides prepared were evaluated for antitubercular activity against M. tuberculosis H37Rv ATCC 27294.

Complete synthesis method of natural product Nostosin B

The invention discloses a complete synthesis method of a natural product Nostosin B, and belongs to the technical field of organic synthesis. According to the synthesis method, complete synthesis of the natural product Nostosin B is completed by natural amino acid L-isoleucine, arginine and a non-natural compound 2 which are cheap and easy to obtain through peptide coupling and using of various of functional group protecting groups. The natural product Nostosin B is prepared through the complete synthesis method for the first time. The synthesis method has the advantages of being simple, convenient, feasible, easy to operate and high in yield.

Stereoselective total synthesis of phenolic nonadecanediol

A simple and highly efficient synthetic route has been developed for synthesis of 1-(4-hydroxyphenyl)nonadecane-3,5-diol (1). The two stereogenic centers were generated by employing proline asymmetric α-hydroxylation (MacMillan α-hydroxylation), Jacobsen's hydrolytic kinetic resolution (HKR), and, finally, Yamaguchi oxirane opening as key steps (Scheme 2). Copyright