946002-05-7

Basic information

• Product Name: (R)-8-hydroxy-3-(4-methoxy-3-(methoxymethoxy)phenyl)-3,4-dihydroisocoumarin
• Synonyms: (R)-8-hydroxy-3-(4-methoxy-3-(methoxymethoxy)phenyl)-3,4-dihydroisocoumarin
• CAS NO: 946002-05-7
• Molecular Weight: 330.337
• Mol File: 946002-05-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (R)-8-hydroxy-3-(4-methoxy-3-(methoxymethoxy)phenyl)-3,4-dihydroisocoumarin(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-8-hydroxy-3-(4-methoxy-3-(methoxymethoxy)phenyl)-3,4-dihydroisocoumarin(946002-05-7)
• EPA Substance Registry System: (R)-8-hydroxy-3-(4-methoxy-3-(methoxymethoxy)phenyl)-3,4-dihydroisocoumarin(946002-05-7)

Safety Data

• Hazardous Substances Data: 946002-05-7(Hazardous Substances Data)

Upstream product

• 946001-97-4 (1R)-2-{2-[(S)-4-isopropyl-4,5-dihydrooxazol-2-yl]-3-methoxyphenyl}-1-(4-methoxy-3-(methoxymethoxy)phenyl)ethanol 
• 6161-65-5 2-methoxy-6-methyl-benzoic acid 
• 50463-84-8 2-methoxy-6-methylbenzoyl chloride 
• 946001-52-1 (S)-4-isopropyl-2-(2-methoxy-6-methylphenyl)-4,5-dihydrooxazole 

Downstream Products

• 21499-23-0 phyllodulcin 

Relevant articles and documents

Asymmetric synthesis of 3-substituted 8-hydroxy-3,4-dihydroisocoumarins from (S)-4-isopropyl-2-(2-methoxy-6-methylphenyl)oxazoline

Reaction of the laterally lithiated (S)-4-isopropyl-2-(2-methoxy-6-methylphenyl)oxazoline with p-tolualdehyde gave an inseparable mixture of the addition products in low diastereoselectivity. However, the (S,S)-product cyclized to the corresponding 3,4-di