50463-84-8Relevant articles and documents
PYRAZOLOPYRIMIDINE DERIVATIVES USEFUL AS INHIBITORS OF BRUTON'S TYROSINE KINASE
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Paragraph 00417-00418, (2016/01/01)
This invention relates to compounds of formula (I). The compounds of the invention are tyrosine kinase inhibitors. Specifically, the compounds of the invention are useful as inhibitors of Bruton's tyrosine kinase (BTK). The invention also contemplates the
Asymmetric synthesis of 3-substituted 8-hydroxy-3,4-dihydroisocoumarins from (S)-4-isopropyl-2-(2-methoxy-6-methylphenyl)oxazoline
Uchida, Katsuya,Fukuda, Tsutomu,Iwao, Masatomo
, p. 7178 - 7186 (2008/02/07)
Reaction of the laterally lithiated (S)-4-isopropyl-2-(2-methoxy-6-methylphenyl)oxazoline with p-tolualdehyde gave an inseparable mixture of the addition products in low diastereoselectivity. However, the (S,S)-product cyclized to the corresponding 3,4-di
Synthetic studies towards the benzophenone precursor for balanol
Patil, Mahesh L.,Deshpande, Vishnu H.,Ramlingam,Borate, Hanumant B.
, p. 1869 - 1873 (2007/10/03)
Synthesis of 4-carboxy-2,6-dimethoxyphenyl 2′-carboxy-6′- methoxyphenyl ketone, an important precursor for balanol's benzophenone portion, has been achieved via a short and efficient route in three steps using ortho-lithiation as the key step. In another
