94693-37-5Relevant articles and documents
First total synthesis of prasinic acid and its anticancer activity
Chakor, Narayan,Patil, Ganesh,Writer, Diana,Periyasamy, Giridharan,Sharma, Rajiv,Roychowdhury, Abhijit,Mishra, Prabhu Dutt
, p. 6608 - 6610 (2013/01/14)
The first total synthesis of prasinic acid is being reported along with its biological evaluation. The ten step synthesis involved readily available and cheap starting materials and can easily be transposed to large scale manufacturing. The crucial steps of the synthesis included the formation of two different aromatic units (7 and 9) and their coupling reaction. The synthetic prasinic acid exhibited moderate antitumor activity (IC50 4.3-9.1 μM) in different lines of cancer cells.
Total syntheses of KS-501, KS-502, and their enantiomers
Dushin,Danishefsky
, p. 655 - 659 (2007/10/02)
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