950524-10-4

Basic information

• Product Name: C₄₀H₄₃FN₂O₅
• Synonyms: C₄₀H₄₃FN₂O₅
• CAS NO: 950524-10-4
• Molecular Weight: 650.79
• Mol File: 950524-10-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₄₀H₄₃FN₂O₅(CAS DataBase Reference)
• NIST Chemistry Reference: C₄₀H₄₃FN₂O₅(950524-10-4)
• EPA Substance Registry System: C₄₀H₄₃FN₂O₅(950524-10-4)

Safety Data

• Hazardous Substances Data: 950524-10-4(Hazardous Substances Data)

Upstream product

• 257628-68-5 N-(2-bromobenzylidene)butan-1-amine 
• 459-46-1 4-Fluorobenzyl bromide 
• 6630-33-7 ortho-bromobenzaldehyde 
• 1535-41-7 1-fluoro-4-(nitromethyl)benzene 
• 950523-94-1 1-bromo-2-(2-nitro-2-(4-fluorophenyl)-vinyl)-benzene 
• 889878-50-6 1-(4-fluoro-phenyl)-2-hydroxymethyl-3-isopropyl-5-phenyl-3,5-dihydro-pyrrolo[2,3-c]quinolin-4-one 
• 889878-49-3 1-(4-fluoro-phenyl)-3-isopropyl-4-oxo-5-phenyl-4,5-dihydro-3H-pyrrolo[2,3-c]quinoline-2-carbaldehyde 
• 889878-48-2 3-(2-bromo-phenyl)-4-(4-fluoro-phenyl)-5-formyl-1-isopropyl-1H-pyrrole-2-carboxylic acid phenylamide 
• 889878-47-1 3-(2-bromo-phenyl)-4-(4-fluoro-phenyl)-5-formyl-1-isopropyl-1H-pyrrole-2-carboxylic acid 
• 889878-46-0 3-(2-bromo-phenyl)-4-(4-fluoro-phenyl)-5-formyl-1-isopropyl-1H-pyrrole-2-carboxylic acid ethyl ester 
• 889878-45-9 3-(2-bromo-phenyl)-4-(4-fluoro-phenyl)-1-isopropyl-1H-pyrrole-2-carboxylic acid ethyl ester 
• 889878-44-8 3-(2-bromo-phenyl)-4-(4-fluoro-phenyl)-1H-pyrrole-2-carboxylic acid ethyl ester 
• 124752-23-4 tert-butyl 2-[(4R,6S)-6-formyl-2,2-dimethyl-1,3-dioxan-4-yl]acetate 

Downstream Products

• 950524-51-3 C₃₇H₃₉FN₂O₅ 
• 950524-53-5 7-[1-(4-fluoro-phenyl)-3-isopropyl-4-oxo-5-phenyl-4,5-dihydro-3H-pyrrolo[2,3-c]quinolin-2-yl]-3,5-dihydroxy-heptanoic acid tert-butyl ester 

Relevant articles and documents

Design and synthesis of novel, conformationally restricted HMG-CoA reductase inhibitors

Using structure-based design, a novel series of conformationally restricted, pyrrole-based inhibitors of HMG-CoA reductase were discovered. Leading analogs demonstrated potent inhibition of cholesterol synthesis in both in vitro and in vivo models and may