951024-70-7

Basic information

• Product Name: (E)-2-hydroxymethyl-3-phenyl-2-propenal
• Synonyms: (E)-2-hydroxymethyl-3-phenyl-2-propenal
• CAS NO: 951024-70-7
• Molecular Weight: 162.188
• Mol File: 951024-70-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (E)-2-hydroxymethyl-3-phenyl-2-propenal(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-2-hydroxymethyl-3-phenyl-2-propenal(951024-70-7)
• EPA Substance Registry System: (E)-2-hydroxymethyl-3-phenyl-2-propenal(951024-70-7)

Safety Data

• Hazardous Substances Data: 951024-70-7(Hazardous Substances Data)

Upstream product

• 120696-98-2 2-hydroxymethyl-3t-phenyl-acrylonitrile 
• 951024-86-5 (E)-2-Diethoxymethyl-3-phenyl-prop-2-en-1-ol 
• 99186-23-9 2-benzylidenepropane-1,3-diol 
• 184175-25-5 (E)-2-(diethoxymethyl)cinnamaldehyde 
• 4364-05-0 (Z)-(2-bromo-3,3-diethoxyprop-1-en-1-yl)benzene 
• 33603-90-6 (2Z)-2-bromo-3-phenyl-2-propenal 
• 14371-10-9 (E)-3-phenylpropenal 

Downstream Products

• 131202-41-0 (E)-3-Phenylmethylene-2-oxetanone 
• 951024-72-9 C₂₃H₂₆O₄ 
• 951024-71-8 C₂₆H₂₉O₅N 
• 131202-40-9 (E)-2-(Hydroxymethyl)-3-phenyl-2-propenoic acid 

Relevant articles and documents

Regioselective TEMPO oxidation of 2-alkylidene-1,3-propanediols to (E)-2-hydroxymethyl-2-alkenals and application to 4-alkylidene-2-penten-5-olide synthesis

The oxidation system comprised of TEMPO and (diacetoxyiodo)benzene (stoichiometric) is enhanced during the conversion of primary alcohols to aldehydes by adding a catalytic amount of acids, p-TsOH and PPTS. 2-Alkylidene-1,3-propanediols, available from 1,3-dihydroxyacetone, are oxidized under the stated conditions to the corresponding (E)-2-hydroxymethyl-2- alkenals, which are utilized as an intermediate for the expeditious synthesis of 4-alkylidene-2-penten-5-olides.

Synthesis and Structure of (E)-3-Phenylmethylene-2-oxetanone: Comments on the Stability of Methylene β-Lactones

A route to stereospecifically (E)-substituted methylene-2-oxetanones is exemplified by the preparation of the phenyl derivative 4, whose structure has been confirmed by a single crystal X-ray structure determination.The relative stability of the parent compound, 3-methylene-2-oxetanone (5) has been compared with that of the well-known 4-methylene-2-oxetanone (6) (ketene dimer), by use of calculations involving Gaussian 82 programs.