95185-43-6Relevant articles and documents
Mapping the ATP-binding domain of DNA-dependent protein kinase (DNA-PK) with coumarin- and isocoumarin-derived inhibitors
Payne, Sara L.,Rodriguez-Aristegui, Sonsoles,Bardos, Julia,Cano, Celine,Golding, Bernard T.,Hardcastle, Ian R.,Peacock, Marcus,Parveen, Nahida,Griffin, Roger J.
scheme or table, p. 3649 - 3653 (2010/09/17)
Replacement of the core heterocycle of a defined series of chromen-4-one DNA-PK inhibitors by the isomeric chromen-2-one (coumarin) and isochromen-1-one (isocoumarin) scaffolds was investigated. Structure-activity relationships for DNA-PK inhibition were broadly consistent, albeit with a reduction of potency compared with the parent chromenone.
A MILD AND FACILE SYNTHESIS OF CARBOXYLIC ANHYDRIDES
Kita, Y.,Akai, S.,Yoshigi, M.,Nakajima, Y.,Yasuda, H.,Tamura, Y.
, p. 6027 - 6030 (2007/10/02)
Reaction of carboxylic acids with trimethylsilylethoxyacetylene in an inert solvent under mild conditions affords the corresponding carboxylic anhydrides in almost quantitative yields.
