952709-03-4

Basic information

• Product Name: ((1R,3S)-3-(t-butoxycarbonylamino)cyclopentyl)((R)-3-((S)-1-hydroxy-5-methoxy-1-(2-phenoxyphenyl)pentyl)piperidin-1-yl)methanone
• Synonyms: ((1R,3S)-3-(t-butoxycarbonylamino)cyclopentyl)((R)-3-((S)-1-hydroxy-5-methoxy-1-(2-phenoxyphenyl)pentyl)piperidin-1-yl)methanone
• CAS NO: 952709-03-4
• Molecular Weight: 580.765
• Mol File: 952709-03-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: ((1R,3S)-3-(t-butoxycarbonylamino)cyclopentyl)((R)-3-((S)-1-hydroxy-5-methoxy-1-(2-phenoxyphenyl)pentyl)piperidin-1-yl)methanone(CAS DataBase Reference)
• NIST Chemistry Reference: ((1R,3S)-3-(t-butoxycarbonylamino)cyclopentyl)((R)-3-((S)-1-hydroxy-5-methoxy-1-(2-phenoxyphenyl)pentyl)piperidin-1-yl)methanone(952709-03-4)
• EPA Substance Registry System: ((1R,3S)-3-(t-butoxycarbonylamino)cyclopentyl)((R)-3-((S)-1-hydroxy-5-methoxy-1-(2-phenoxyphenyl)pentyl)piperidin-1-yl)methanone(952709-03-4)

Safety Data

• Hazardous Substances Data: 952709-03-4(Hazardous Substances Data)

Upstream product

• 163438-09-3 (R)-1-Boc-nipecotic acid 
• 634590-61-7 (4-methoxybutyl)magnesium chloride 
• 884512-19-0 (3R)-1-(tert-butoxycarbonyl)-3-(2-phenoxybenzoyl)piperidine 
• 884510-86-5 (R)-tert-butyl 3-(methoxy(methyl)carbamoyl)piperidine-1-carboxylate 
• 161660-94-2 (1R,3S)-3-((tert-butoxycarbonyl)amino)cyclopentane-1-carboxylic acid 

Relevant articles and documents

Biphenyl/diphenyl ether renin inhibitors: Filling the S1 pocket of renin via the S3 pocket

Structure-based design led to the discovery of a novel class of renin inhibitors in which an unprecedented phenyl ring filling the S1 site is attached to the phenyl ring filling the S3 pocket. Optimization for several parameters including potency in the p