952755-85-0

Basic information

• Product Name: (R)-(+)-4-methyl-3-phenyl-1-pentanol
• Synonyms: (R)-(+)-4-methyl-3-phenyl-1-pentanol
• CAS NO: 952755-85-0
• Molecular Weight: 178.274
• Mol File: 952755-85-0.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: (R)-(+)-4-methyl-3-phenyl-1-pentanol(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-(+)-4-methyl-3-phenyl-1-pentanol(952755-85-0)
• EPA Substance Registry System: (R)-(+)-4-methyl-3-phenyl-1-pentanol(952755-85-0)

Safety Data

• Hazardous Substances Data: 952755-85-0(Hazardous Substances Data)

Upstream product

• 54784-84-8 4-Methyl-3-phenylpentanal 
• 55001-04-2 (+/-)-4-methyl-3-phenyl-1-pentanol 
• 309270-97-1 (Z)-4-methyl-3-phenyl-2-penten-1-ol 
• 4392-24-9 Cinnamyl bromide 
• 18713-58-1 1-(4-chlorophenyl)-2-methylpropan-1-one 
• 51690-50-7 4-methyl-3-phenylpentanoic acid 
• 140-10-3 (E)-3-phenylacrylic acid 
• 75834-17-2 (3S)-(-)-4-Methyl-3-phenylpentanal 
• 309270-99-3 (E)-4-methyl-3-phenyl-2-penten-1-ol 
• 126275-08-9 (E)-3-(4-Chloro-phenyl)-4-methyl-pent-2-enoic acid ethyl ester 
• 75834-11-6 (S)-(-)-1-Cinnamyl-(2-methoxymethyl)pyrrolidin 

Relevant articles and documents

Asymmetric hydrogenation of allylic alcohols using ir?N,P-Complexes

In this study, a series of γ,γ-disubstituted and β,γ-disubstituted allylic alcohols were prepared and successfully hydrogenated using suitable N,P-based Ir complexes. High yields and excellent enantioselectivities were obtained for most of the substrates studied. This investigation also revealed the effect of the acidity of the N,P?Ir-complexes on the acid-sensitive allylic alcohols. DFT ΔpKa calculations were used to explain the effect of the N,P-ligand on the acidity of the corresponding Ir-complex. The selectivity model of the reaction was used to accurately predict the absolute configuration of the hydrogenated alcohols.

Regio- and diastereoselective conjugate addition of Grignard reagents to aryl substituted α,β-unsaturated carbonyl compounds derived from Oppolzer's sultam

Asymmetric conjugate addition of Grignard reagents to aryl substituted α,β-unsaturated carbonyl compounds (1) has been achieved with great regioselectivity (>20:1) and good to excellent diastereoselectivity (de up to 98%). The nucleophilicity and stereospecific blockade of the Grignard reagents play a key role in controlling the regioselectivities and diastereoselectivities of the conjugate addition reaction.

A versatile new catalyst for the enantioselective isomerization of allylic alcohols to aldehydes: Scope and mechanistic studies

A new planar-chiral bidentate phosphaferrocene ligand (2) has been synthesized and structurally characterized. The derived rhodium complex, [Rh(cod)(2)]BF4, serves as an effective catalyst for asymmetric isomerizations of allylic alcohols to aldehydes, furnishing improved yields, scope, and enantioselectivities relative to previously reported methods. The catalyst is air-stable and can be recovered at the end of the reaction. Mechanistic studies establish that the isomerization proceeds via an intramolecular 1,3-hydrogen migration and that the catalyst differentiates between the enantiotopic C1 hydrogens.