55001-04-2Relevant articles and documents
Enantioselective halogenative semi-pinacol rearrangement: A stereodivergent reaction on a racemic mixture
Romanov-Michailidis, Fedor,Pupier, Marion,Gune, Laure,Alexakis, Alexandre
, p. 13461 - 13464 (2015/02/19)
An efficient, quantitative deracemization strategy for optically inactive allylic cycloalkanols has been achieved using the biphasic halogenative semi-pinacol reaction protocol. The resultant β-halo spiroketones, containing three contiguous stereogenic ce
Lipase catalyzed acylation of primary alcohols with remotely located stereogenic centres: the resolution of (±)-4,4-dimethyl-3-phenyl-1-pentanol
Sabbani, Sunil,Hedenstroem, Erik,Andersson, Jimmy
, p. 1712 - 1720 (2008/02/11)
Enantioselective acylation of some (±)-3-alkyl-3-phenyl-1-propanols was performed with enzymes as catalysts. Moderate enantiomeric ratios (E), ranging up to E = 11.6, were obtained. In the resolution, some of the lipases selectively acylated the (+)-enant
Generation of γ-oxy-substituted benzylithium derivatives by reductive lithiation of 4-phenyl-1,3-dioxanes
Azzena, Ugo,Pilo, Luciano
, p. 664 - 668 (2007/10/03)
Reductive cleavage of 1,3-dioxanes 1a-c with Li metal in the presence of a catalytic amount of naphthalene in THF, followed by reaction with different electrophiles, allowed the synthesis of 3-substituted- and 3,3-disubstituted- 3-phenylpropan-1-ols 4 in good yields.