95363-37-4

Basic information

• Product Name: 9-O-Benzoylretronecine
• Synonyms: 9-O-Benzoylretronecine
• CAS NO: 95363-37-4
• Molecular Weight: 259.305
• Mol File: 95363-37-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 9-O-Benzoylretronecine(CAS DataBase Reference)
• NIST Chemistry Reference: 9-O-Benzoylretronecine(95363-37-4)
• EPA Substance Registry System: 9-O-Benzoylretronecine(95363-37-4)

Safety Data

• Hazardous Substances Data: 95363-37-4(Hazardous Substances Data)

Upstream product

• 98-88-4 benzoyl chloride 
• 480-85-3 retronecine 
• 315-22-0 monocrotaline 
• 65-85-0 benzoic acid 

Downstream Products

• 126191-55-7 (5R)-1-Aza-3(R)-phenyl-4(S)-(benzoylmethyl)-4(S)-carboxy-6(R)-hydroxybicyclo<3.3.0>octane Lactone 
• 520-63-8 (+)-heliotridine 
• 25471-42-5 (7aR)-1c-benzoyloxy-7-benzoyloximethyl-(7ar)-2,3,5,7a-tetrahydro-1H-pyrrolizin 
• 99612-73-4 Benzoic acid (7S,7aR)-7-((E)-2-methyl-but-2-enoyloxy)-5,6,7,7a-tetrahydro-3H-pyrrolizin-1-ylmethyl ester 
• 99629-53-5 Benzoic acid (7S,7aR)-7-((Z)-2-methyl-but-2-enoyloxy)-5,6,7,7a-tetrahydro-3H-pyrrolizin-1-ylmethyl ester 
• 99612-72-3 Benzoic acid (7S,7aR)-7-propionyloxy-5,6,7,7a-tetrahydro-3H-pyrrolizin-1-ylmethyl ester 
• 99612-71-2 Benzoic acid (7S,7aR)-7-acetoxy-5,6,7,7a-tetrahydro-3H-pyrrolizin-1-ylmethyl ester 
• 6870-33-3 Benzoic acid (7R,7aR)-7-hydroxy-4-oxy-5,6,7,7a-tetrahydro-3H-pyrrolizin-1-ylmethyl ester 
• 126191-53-5 7-O-(Phenoxythiocarbonyl)-9-O-benzoylretronecine 
• 99612-70-1 Benzoic acid (7R,7aR)-7-methanesulfonyloxy-5,6,7,7a-tetrahydro-3H-pyrrolizin-1-ylmethyl ester 
• 25471-42-5 7,ω-Di-O-benzoylretronecin 

Relevant articles and documents

Synthesis of pyrrolizidine alkaloids indicine, intermedine, lycopsamine, and analogues and their N-oxides. Potential antitumor agents

(-)- and (+)-trachelanthic and (-)- and (+)-viridifloric acids were synthesized and their isopropylidene derivatives were regiospecifically coupled, at C-9, with (-)-retronecine (2) obtained by hydrolysis of monocrotaline (1), isolated from Crotalaria spectabilis. Hydrolysis, followed by oxidation, led to the N-oxides of indicine (7), intermedine (13), lycopsamine (15), and the new nonnatural product 16, respectively. Each of these analogues was screened in the P388 lymphocytic leukemia system at the same time as indicine N-oxide, and the results were compared. Other related analogues were prepared and similarly screened and the results compared with those from indicine N-oxide.