958227-62-8

Basic information

• Product Name: 4-[4-((1R,2S)-2-isopropylcarbamoyl-cyclopentylamino)-5-trifluoromethyl-pyrimidin-2-ylamino]-2-ethoxybenzoic acid
• Synonyms: 4-[4-((1R,2S)-2-isopropylcarbamoyl-cyclopentylamino)-5-trifluoromethyl-pyrimidin-2-ylamino]-2-ethoxybenzoic acid
• CAS NO: 958227-62-8
• Molecular Weight: 495.502
• Mol File: 958227-62-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-[4-((1R,2S)-2-isopropylcarbamoyl-cyclopentylamino)-5-trifluoromethyl-pyrimidin-2-ylamino]-2-ethoxybenzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-[4-((1R,2S)-2-isopropylcarbamoyl-cyclopentylamino)-5-trifluoromethyl-pyrimidin-2-ylamino]-2-ethoxybenzoic acid(958227-62-8)
• EPA Substance Registry System: 4-[4-((1R,2S)-2-isopropylcarbamoyl-cyclopentylamino)-5-trifluoromethyl-pyrimidin-2-ylamino]-2-ethoxybenzoic acid(958227-62-8)

Safety Data

• Hazardous Substances Data: 958227-62-8(Hazardous Substances Data)

Upstream product

• 1036488-09-1 (1S,2R)-2-(2-chloro-5-trifluoromethyl-pyrimidin-4-ylamino)-cyclopentanecarboxylic acid isopropylamide 
• 59-07-4 2-ethoxy-4-aminobenzoic acid 

Downstream Products

• 958227-71-9 2-ethoxy-4-[4-((1R,2S)-2-isopropylcarbamoyl-cyclopentylamino)-5-trifluoromethyl-pyrimidin-2-ylamino]-N-methyl-N-(1-methyl-piperidin-4-yl)-benzamide 

Relevant articles and documents

New compounds

The present invention encompasses compounds of general formula (1) wherein R1, R2, R4, X, m, n and p are defined as in claim 1, which are suitable for the treatment of diseases characterised by excessive or abnormal cell proliferation, and their use for preparing a pharmaceutical composition having the above-mentioned properties.