958233-17-5Relevant articles and documents
Radioactive molecular probe taking TSPO as target point as well as preparation method and application thereof
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, (2020/05/30)
The invention discloses a small molecular organic compound with a specific targeting TSPO (Transfer Protein). The structure of the small molecular organic compound comprises a benzene ring, pyrazolo imidazole and a diethyl acetamide structure. The P-tolue
Microwave-assisted organic synthesis of a high-affinity pyrazolo-pyrimidinyl TSPO ligand
Tang, Dewei,Buck, Jason R.,Hight, Matthew R.,Manning, H. Charles
supporting information; experimental part, p. 4595 - 4598 (2010/09/18)
We herein report a dramatically improved total synthesis of the high-affinity translocator protein (TSPO) ligand DPA-714, featuring microwave-assisted organic synthesis (MAOS). Compared with previously described approaches, our novel MAOS method dramatica
Synthesis and biological evaluation of substituted [18F] imidazo[1,2-a]pyridines and [18F]pyrazolo[1,5-a]pyrimidines for the study of the peripheral benzodiazepine receptor using positron emission tomography
Fookes, Christopher J. R.,Pham, Tien Q.,Mattner, Filomena,Greguric, Ivan,Loc'h, Christian,Liu, Xiang,Berghofer, Paula,Shepherd, Rachael,Gregoire, Marie-Claude,Katsifis, Andrew
experimental part, p. 3700 - 3712 (2009/04/11)
The fluoroethoxy and fluoropropoxy substituted 2-(6-chloro-2-phenyl) imidazo[1,2-a]pyridin-3-yl)-N,N-diethylacetamides 8 (PBR102) and 12 (PBR111) and 2-phenyl-5,7-dimethylpyrazolo[1,5-a]pyrimidin-3-yl)-N,N-diethylacetamides 15 (PBR099) and 18 (PBR146) wer