958707-54-5

Basic information

• Product Name: 7'-methoxy-5'H-spiro[piperidine-4,4'-pyrrolo[1,2-a]quinoxaline]
• Synonyms: 7'-methoxy-5'H-spiro[piperidine-4,4'-pyrrolo[1,2-a]quinoxaline]
• CAS NO: 958707-54-5
• Molecular Weight: 269.346
• Mol File: 958707-54-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 7'-methoxy-5'H-spiro[piperidine-4,4'-pyrrolo[1,2-a]quinoxaline](CAS DataBase Reference)
• NIST Chemistry Reference: 7'-methoxy-5'H-spiro[piperidine-4,4'-pyrrolo[1,2-a]quinoxaline](958707-54-5)
• EPA Substance Registry System: 7'-methoxy-5'H-spiro[piperidine-4,4'-pyrrolo[1,2-a]quinoxaline](958707-54-5)

Safety Data

• Hazardous Substances Data: 958707-54-5(Hazardous Substances Data)

Upstream product

• 96-96-8 4-methoxy-2-nitroaniline 
• 59194-25-1 1H–1–(4–methoxy–2–nitrophenyl)pyrrole 
• 1259381-02-6 benzyl 7'-methoxy-5'H-spiro[piperidine-4,4'-pyrroIo[1,2-a]quinoxaline]-1-carboxylate 
• 59194-26-2 2–(1H–pyrrol–1–yl)–5–methoxyaniline 
• 41979-39-9 4-piperidone hydrochloride 

Downstream Products

• 1259377-50-8 (3,5-dimethoxyphenyl)(7'-methoxy-5'H-spiro[piperidine-4,4'-pyrrolo[1,2-a]quinoxaline]-1-yl)methanone hydrochloride 
• 1189967-05-2 C₂₄H₂₂N₄O₂ 
• 1259378-47-6 C₂₄H₂₂N₄O₂ 
• 1184997-31-6 7'-methoxy-1-[4-(2,2,2-trifluoroethoxy)benzoyl]spiro[piperidine-4,4'(5'H)-pyrrolo[1,2-a]quinoxaline] 
• 1259378-43-2 C₂₅H₂₈N₄O₂ 
• 1259380-66-9 1-[3-(dimethylamino)-4-methoxybenzoyl]-7'-methoxyspiro[piperidine-4,4'(5'H)-pyrrolo[1,2-a]quinoxaline] 

Relevant articles and documents

Discovery of pyrrolo-benzo-1,4-diazines as potent Nav1.7 sodium channel blockers

A series of pyrrolo-benzo-1,4-diazine analogs have been synthesized and displayed potent Nav1.7 inhibitory activity and moderate selectivity over Nav1.5. The syntheses, structure-activity relationships, and selected pharmacokinetic data of these analogs are described. Compound 41 displayed anti-nociceptive efficacy in the rat CFA pain model at 100 mpk oral dosing.