96439-99-5

Basic information

• Product Name: Pyridine, 3-bromo-2-ethynyl-
• CAS NO: 96439-99-5
• Molecular Formula: C7H4BrN
• Mol File: 96439-99-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Pyridine, 3-bromo-2-ethynyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Pyridine, 3-bromo-2-ethynyl-(96439-99-5)
• EPA Substance Registry System: Pyridine, 3-bromo-2-ethynyl-(96439-99-5)

Safety Data

• Hazardous Substances Data: 96439-99-5(Hazardous Substances Data)

Upstream product

• 13534-89-9 2,3-dibromopyridine 
• 1066-54-2 trimethylsilylacetylene 

Relevant articles and documents

Reductive Amination of Ethynylpyridines with Sodium Cyanoborohydride

In order to investigate the structure-activity relationship of betahistine derivatives, a general synthesis of methylated 2-(2-methylaminoethyl)pyridines was developed based on the addition of methylamine hydrochloride to methylated 2-ethynylpyridines under reductive conditions.In addition, the scope and limitations of the reductive addition were briefly examined.For example, the reaction proceeded smoothly with p-nitrophenylacetylene, whereas phenylacetylene itself did not react with methylamine.Keywords - ethynylpyridine; sodium cyanoborohydride; reductive amination; betahistine; palladium-catalyzed reaction; ethyl pyridineacetate; 2-(2-pyridyl)ethylamine