96838-39-0

Basic information

• Product Name: (S)-2-benzyloxycarbonylamino-3-(2-methylthio-3-indolyl)propanoic acid
• Synonyms: (S)-2-benzyloxycarbonylamino-3-(2-methylthio-3-indolyl)propanoic acid
• CAS NO: 96838-39-0
• Molecular Weight: 384.456
• Mol File: 96838-39-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (S)-2-benzyloxycarbonylamino-3-(2-methylthio-3-indolyl)propanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-2-benzyloxycarbonylamino-3-(2-methylthio-3-indolyl)propanoic acid(96838-39-0)
• EPA Substance Registry System: (S)-2-benzyloxycarbonylamino-3-(2-methylthio-3-indolyl)propanoic acid(96838-39-0)

Safety Data

• Hazardous Substances Data: 96838-39-0(Hazardous Substances Data)

Upstream product

• 2279-15-4 carbobenzyloxy-L-trytophan 
• 110527-66-7 methyl 2-benzyloxycarbonylamino-3-(2-thioxo-3-indolinyl)propanoate 
• 911675-22-4 (S)-2-(((benzyloxy)carbonyl)amino)-3-(2-oxoindolin-3-yl)propanoic acid 
• 96838-38-9 methyl (S)-2-benzyloxycarbonylamino-3-(2-methylthio-3-indolyl)propanoate 
• 96838-37-8 methyl (S)-2-benzyloxycarbonylamino-3-((RS)-2-oxo-3-indolinyl)propanoate 

Downstream Products

• 96838-41-4 (R)-2-[(S)-2-Benzyloxycarbonylamino-3-(2-methylsulfanyl-1H-indol-3-yl)-propionylamino]-3-(2-methylsulfanyl-1H-indol-3-yl)-propionic acid methyl ester 

Relevant articles and documents

TOTAL SYNTHESIS OF AMAUROMINE

A total synthesis of amauromine (1) is described.Starting with L-tryptophan, diketopiperazine 4 was synthesized in nine steps.Thio-Claisen rearrangement of the sulphonium cation derived from the key intermediate 4 proceeded at the two sites simultaneously to provide 3 along with 12.Reductive desulphurization on 3 using TiCl4-LiAlH4 (1:2) resulted in concurrent cyclization to lead to amauromine (1).