97024-55-0

Basic information

• Product Name: Methyl-<4-(4-methoxy-phenyl)-pent-4-enoat>
• Synonyms: Methyl-<4-(4-methoxy-phenyl)-pent-4-enoat>
• CAS NO: 97024-55-0
• Molecular Weight: 220.268
• Mol File: 97024-55-0.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: Methyl-<4-(4-methoxy-phenyl)-pent-4-enoat>(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl-<4-(4-methoxy-phenyl)-pent-4-enoat>(97024-55-0)
• EPA Substance Registry System: Methyl-<4-(4-methoxy-phenyl)-pent-4-enoat>(97024-55-0)

Safety Data

• Hazardous Substances Data: 97024-55-0(Hazardous Substances Data)

Upstream product

• 3153-44-4 4-(4-methoxy-phenyl)-4-oxo-butyric acid 
• 3878-55-5 methyl hydrogen succinate 
• 5720-07-0 4-methoxyphenylboronic acid 
• 194805-62-4 methyl-4-bromo-pent-4-enoate 
• 5447-74-5 methyl 3-(4-methoxybenzoyl)propionate 
• 1779-49-3 Methyltriphenylphosphonium bromide 
• 19493-09-5 Methylenetriphenylphosphorane 

Downstream Products

• 398142-14-8 4-(4-methoxy-phenyl)-4-pentenoic acid 
• 1254701-70-6 (S)-5-(bromomethyl)-5-(4-methoxyphenyl)dihydrofuran-2(3H)-one 
• 4518-13-2 methyl 2-(2-(4-methoxyphenyl)-5-oxotetrahydrofuran-2-yl)acetate 
• 127047-19-2 4-(4-methoxyphenyl)pent-4-en-1-ol 
• 1304754-88-8 (R)-2-(bromomethyl)-2-(4-methoxyphenyl)-1-(4-nitrophenylsulfonyl)pyrrolidine 
• 1304754-11-7 4-nitro-N-(4-(4-methoxyphenyl)-4-pentenyl)benzenesulfonamide 
• 121943-56-4 methyl 4-(4-methoxyphenyl)pentanoate 

Relevant articles and documents

Electrochemical [4+2] Annulation-Rearrangement-Aromatization of Styrenes: Synthesis of Naphthalene Derivatives

We report the first electrochemical strategy to synthesize functionalized naphthalene derivatives through [4+2] annulation—rearrangement–aromatization from styrenes under mild conditions. The electrolysis does not require metals, oxidants and high valence substrates, indicating the atom and step-economy ideals. The dehydrodimer produced through [4+2] cycloaddition of 4-methoxy α-methyl styrene is isolated and proved to be the key intermediate for the following oxydehydrogenation to form carbon cation, which undergoes rearrangement–aromatization to afford the final products. This reaction represents a powerful access to construct multi-substituted naphthalene blocks in a single step.

Electrophilic Bromolactonization of Cyclopropyl Carboxylic Acids Using Lewis Basic Sulfide Catalyst

A highly facile and efficient electrophilic bromolactonization of cyclopropylcarboxylic acids could be effected by a Lewis basic sulfide catalyst. Mechanistic studies performed revealed that the cyclopropane substrates could undergo radical bromination upon exposure to light, yielding a mixture of regioisomers. In stark contrast, the Lewis basic sulfide catalyst could promote the electrophilic bromolactonization and yield the Markovnikov product exclusively.

Asymmetric bromolactonization using amino-thiocarbamate catalyst

A novel amino-thiocarbamate-catalyzed bromolactonization of unsaturated carboxylic acids has been developed. The scope of the reaction is evidenced by 22 examples of γ-lactones with up to 99% yield and 93% ee. The protocol was applied in the enantioselective synthesis of the key intermediates of VLA-4 antagonists.