97254-91-6Relevant articles and documents
Syntheses of tetrahydroisoquinoline derivatives that inhibit NO production in activated BV-2 microglial cells
Seo, Jai Woong,Srisook, Ekaruth,Son, Hyo Jin,Hwang, Onyou,Cha, Young-Nam,Chi, Dae Yoon
, p. 1160 - 1170 (2008/09/20)
Seventeen tetrahydroisoquinoline derivatives were designed, synthesized and evaluated for inhibition of NO production in lipopolysaccharide-stimulated BV-2 microglial cells. Compounds 5a, 9c and 11a potently attenuated NO production by >60%, and 5a and 11