98154-55-3

Basic information

• Product Name: dimethyl-((1RS,2RS)-1-methyl-2-phenyl-propyl)-amine
• CAS NO: 98154-55-3
• Molecular Weight: 177.29
• Mol File: 98154-55-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: dimethyl-((1RS,2RS)-1-methyl-2-phenyl-propyl)-amine(CAS DataBase Reference)
• NIST Chemistry Reference: dimethyl-((1RS,2RS)-1-methyl-2-phenyl-propyl)-amine(98154-55-3)
• EPA Substance Registry System: dimethyl-((1RS,2RS)-1-methyl-2-phenyl-propyl)-amine(98154-55-3)

Safety Data

• Hazardous Substances Data: 98154-55-3(Hazardous Substances Data)

Upstream product

• 51-64-9 dexamfetamine 
• 17279-39-9 (S)-N,N-dimethyl-α-benzylethylamine 
• 74-88-4 methyl iodide 
• 1823-91-2 1-phenylethyl cyanide 
• 769-59-5 3-phenyl-butan-2-one 
• 50-00-0 formaldehyd 
• 21906-17-2 1,2-trans-dimethyl-2-phenylethylamine 

Relevant articles and documents

THE HIGHLY STEREOSELECTIVE CONVERSION OF N,N-DIMETHYLAMPHETAMINE INTO N-METHYLPSEUDOEPHEDRINE; A MIMIC OF THE ENZYME MEDIATED STEREOSPECIFIC BENZYLIC HYDROXYLATION OF 2-ARYLETHYLAMINES

Treatment of (S)-(η6-N,N-dimethylamphetamine)Cr(CO)3, with n-butyllithium below -40 deg C gives a stable benzylic carbanion via loss of the pro-R-benzylic proton.Warming of this anion above -40 deg C gives (η6-E-β-methylstyrene)Cr(CO), via an ElcB type elimination wilhst trapping with an electrophile below -40 deg C gives benzylically functionalised amphetamines with overall retention of configuration.The use of oxodiperoxymolybdenum(pyridine)hexamtehylphosphoramide as the electrophile gives optically pure (1S,2S)-N-methylpseudoephedrine after decomplexation.