99254-50-9

Basic information

• Product Name: β-(2-iodo-5-methoxyphenyl)propionic acid
• Synonyms: β-(2-iodo-5-methoxyphenyl)propionic acid
• CAS NO: 99254-50-9
• Molecular Weight: 306.1
• Mol File: 99254-50-9.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: β-(2-iodo-5-methoxyphenyl)propionic acid(CAS DataBase Reference)
• NIST Chemistry Reference: β-(2-iodo-5-methoxyphenyl)propionic acid(99254-50-9)
• EPA Substance Registry System: β-(2-iodo-5-methoxyphenyl)propionic acid(99254-50-9)

Safety Data

• Hazardous Substances Data: 99254-50-9(Hazardous Substances Data)

Upstream product

• 10516-71-9 3-(3-Methoxy-phenyl)-propionic acid 
• 54413-93-3 2-iodo-5-methoxybenzoic acid 
• 139557-96-3 (2-iodo-5-methoxyphenyl)methanol 
• 2033-24-1 cycl-isopropylidene malonate 
• 77287-58-2 2-iodo-5-methoxybenzaldehyde 

Downstream Products

• 100634-41-1 N-[2-(3,4-dimethoxyphenyl)ethyl]-2-(1-hexynyl)-5-methoxy-N-methylbenzenepropanamine 
• 100634-48-8 2-(Butynyl)-N-[2-(3,4-dimethoxyphenyl)ethyl]-5-methoxy-N-methylbenzenepropanamine 
• 99254-62-3 N-[2-(3,4-dimethoxyphenyl)ethyl]-2-iodo-5-methoxy-N-methylbenzenepropanamine 
• 99540-59-7 3-[5-Methoxy-2-(phenylethynyl)phenyl]-N,N-dimethylpropanamine 
• 112399-39-0 [3-(2-Iodo-5-methoxy-phenyl)-propyl]-dimethyl-amine 
• 100634-45-5 N-[2-(3,4-Dimethoxyphenyl)ethyl]-5-methoxy-N-methyl-2-(4-phenyl-1-butynyl)benzenepropanamine 
• 99254-56-5 N-<2-(3,4-dimethoxyphenyl)ethyl>-2-iodo-5-methoxy-N-methylbenzenepropanamide 
• 99540-24-6 2-iodo-5-methoxy-N,N-dimethylbenzenepropanamide 
• 250687-92-4 N-(3-hydroxy-4-methoxyphenethyl)-3-(2-iodo-5-methoxyphenyl)propionamide 
• 99254-55-4 2-iodo-5-methoxybenzenepropanoyl chloride 

Relevant articles and documents

Synthesis of N-Glycosyl-2-oxindoles by Pd-Catalyzed N-Arylation of 1-Amidosugars

An efficient intramolecular Pd-catalyzed N-arylation of o-iodo-amidosugars for the synthesis of N-glycosylated oxindoles has been reported. The coupling reaction takes place in toluene and involves Pd(OAc)2/RuPhos catalytic systems in the presence of K2CO3. This versatile approach was extended successfully to the synthesis of other N-glycosylated heterocycles.

Methods for the treatment of hypertension

Acetylene compounds of the formula (I): STR1 wherein Y, R1, R2, R3, and R4 are as described herein, m is 0-3, n is 0-2 and Ar is phenyl or an aromatic heterocycle are disclosed. The compounds possess antihyperte

Aralykyl (arylethynyl)aralkyl amines and their use as vasodilators and antihypertensives

Acetylenes of the formula (I): STR1 wherein Y, m, R1, R2 q, Alk, R3, n and R4 are as defined herein and Ar1 and Ar2 are aromatic, including the salts and ammonium derivatives of formula (I), in treating angina, hypertension and cardiac arrhythmias. Pharmaceutical compositions, methods of use and synthesis and novel intermediates are also part of the invention.