99314-44-0

Basic information

• Product Name: 3-METHYL-3-(TOLUENESULFONYLOXYMETHYL)OXETANE
• Synonyms: 3-METHYL-3-OXETANEMETHANOL P-TOLUENESULFONATE;3-METHYL-3-(TOLUENESULFONYLOXYMETHYL)OXETANE;(3-methyl-3-oxetanyl)methyl 4-methylbenzenesulfonate;(3-Methyloxetan-3-yl)Methyl p-tosylate;3-Methyl-3-(p-toluenesulfonyloxyMethyl)oxetane, 98%;(3-Methyloxetan-3-yl)Methyl 4-Methylbenzenesulfonate;(3-Methyloxetan-3-yl)
• CAS NO: 99314-44-0
• Molecular Formula: C₁₂H₁₆O₄S
• Molecular Weight: 256.32
• Mol File: 99314-44-0.mol
• Article Data: 40

Chemical Properties

• Melting Point: 50-51°
• Boiling Point: 381.12 °C at 760 mmHg
• Flash Point: 184.295 °C
• Appearance: Off-white/Solid
• Density: 1.219 g/cm³
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 3-METHYL-3-(TOLUENESULFONYLOXYMETHYL)OXETANE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-METHYL-3-(TOLUENESULFONYLOXYMETHYL)OXETANE(99314-44-0)
• EPA Substance Registry System: 3-METHYL-3-(TOLUENESULFONYLOXYMETHYL)OXETANE(99314-44-0)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 99314-44-0(Hazardous Substances Data)

Usage

General Description

3-METHYL-3-(TOLUENESULFONYLOXYMETHYL)OXETANE is a chemical compound with the molecular formula C12H16O4S. It is a toluenesulfonyloxymethyl oxetane derivative, which is commonly used as a monomer or crosslinking agent in the production of polymers and resins, specifically in the field of dental materials and adhesives. 3-METHYL-3-(TOLUENESULFONYLOXYMETHYL)OXETANE has the potential to enhance the mechanical properties and improve the overall performance of the final product when incorporated into various polymer systems. It is known for its ability to provide excellent adhesion and resistance to moisture, making it a valuable component in the development of advanced materials for various industrial and medical applications.

Upstream product

• 3143-02-0 3-hydroxymethyl-3-methyloxethane 
• 98-59-9 p-toluenesulfonyl chloride 

Downstream Products

• 141100-23-4 bis-(3-methyloxetan-3-ylmethyl) ether 
• 84051-81-0 3-methyl-3-(nitroxymethyl)oxetane 
• 114644-08-5 Dimethyl-(3-methyl-oxetan-3-ylmethyl)-amine 
• 198572-36-0 1-(3-Methyl-oxetan-3-ylmethyl)-pyrrolidine-2,5-dione 
• 198572-37-1 1-(3-Methyl-oxetan-3-ylmethyl)-piperidine-2,6-dione 
• 206191-47-1 (2S,3R)-2-tert-Butoxycarbonylamino-3-hydroxy-butyric acid 3-methyl-oxetan-3-ylmethyl ester 
• 206191-42-6 (S)-(3-methyloxetan-3-yl)methyl 2-(((benzyloxy)carbonyl)-amino)-3-hydroxypropanoate 
• 206191-43-7 (S)-2-tert-Butoxycarbonylamino-3-hydroxy-propionic acid 3-methyl-oxetan-3-ylmethyl ester 
• 78385-26-9 3-bromomethyl-3-methyloxetane 
• 402578-38-5 (S)-3-Hydroxy-2-(2-nitro-benzenesulfonylamino)-propionic acid 3-methyl-oxetan-3-ylmethyl ester 
• 112823-30-0 3-(iodomethyl)-3-methyl-oxetane 
• 497870-37-8 ethyl 3-(3-methyloxetan-3-yl)propionate 
• 497870-42-5 2-(3-methyloxetan-3-ylmethoxy)-1-phenylethanone 
• 497870-36-7 diethyl 2-(3-methyloxetan-3-ylmethyl)malonate 

Relevant articles and documents

Synthesis and characterization of [60]fullerene-poly(3-azidomethyl-3-methyl oxetane) and its thermal decomposition

A new functionalized fullerene derivative, [60]fullerene-poly(3-azidomethyl-3-methyl oxetane) (C60-PAMMO), was synthesized for the first time using a modified Bingel reaction with [60]fullerene (C60) and bromomalonic acid poly(3-azidomethyl-3-methyl oxetane) ester (BM-PAMMO). The product was characterized by Fourier transform infrared (FTIR), ultraviolet-visible (UV-vis), and nuclear magnetic resonance (NMR) spectroscopy analyses. The results confirmed the successful preparation of C60-PAMMO. Moreover, the thermal decomposition of C60-PAMMO was analyzed by differential scanning calorimetry (DSC), thermogravimetric analysis coupled with infrared spectroscopy (TG-IR), and in situ FTIR spectroscopy. The decomposition of C60-PAMMO showed a three-step thermal process. The first step at approximately 150 °C was related to the cycloaddition of the azido groups (-N3) with [60]fullerene. The second step was ascribed to the decomposition of the remaining PAMMO main chain at approximately 320 °C. The final step was attributed to the burning decomposition of amorphous carbon, the main chain, N-heterocyclic components and the carbon cage around 510 °C.

A bifunctional dimethylsulfoxide substitute enhances the aqueous solubility of small organic molecules

An oxetane-substituted sulfoxide has demonstrated potential as a dimethylsulfoxide substitute for enhancing the dissolution of organic compounds with poor aqueous solubilities. This sulfoxide may find utility in applications of library storage and biological assays. For the model compounds studied, significant solubility enhancements were observed using the sulfoxide as a cosolvent in aqueous media. Brine shrimp, breast cancer (MDA-MB-231), and liver cell line (HepG2) toxicity data for the new additive are also presented, in addition to comparative IC50 values for a series of PKD1 inhibitors.

PYRIDINE DERIVATIVE AS ASK1 INHIBITOR AND PREPARATION METHOD AND USE THEREOF

Disclosed in the present invention are a compound as shown in formula (II), a tautomer or a pharmaceutically acceptable salt thereof, and also disclosed is the use thereof in preparing a drug for treating an ASK1-associated disease.

DIHYDROQUINOLIZINONES AS ANTIVIRALS

Compounds, specifically hepatitis B virus and/or hepatitis D virus inhibitors, more specifically compounds that inhibit HBe antigen and HBs antigen in a subject, for the treatment of viral infections, and methods of preparing and using such compounds. Formula (I):