99522-22-2Relevant articles and documents
Nickel-Catalyzed Csp2-Csp3 Bond Formation via C-F Bond Activation
Ho, Yee Ann,Leiendecker, Matthias,Liu, Xiangqian,Wang, Chengming,Alandini, Nurtalya,Rueping, Magnus
supporting information, p. 5644 - 5647 (2018/09/12)
A nickel-catalyzed cross coupling of aryl fluorides via C-F bond activation has been developed. The alkylation method allows selective replacement of aryl fluorides by alkyl groups and enables the synthesis of diverse and otherwise difficult to access scaffolds in good yields.
Direct oxidation of the C(sp2)-C(sp3) bond from benzyltrimethylsilanes to phenols
Li, Wei,Gao, Guolin,Gao, Yuan,Yang, Chao,Xia, Wujiong
supporting information, p. 5291 - 5293 (2017/07/10)
A novel pathway for direct conversion of benzylsilanes to phenols by oxidation with Na2S2O8 and oxygen is efficiently developed under mild and neutral conditions. The reaction shows good functional group tolerance to afford phenols in moderate yields. The possible mechanism is proposed based on the isotopic labeling trials.
Palladium-catalyzed C(sp 3)-C(sp 2) cross-coupling of (trimethylsilyl)methyllithium with (hetero)aryl halides
Heijnen, Dorus,Hornillos, Valentín,Corbet, Brian P.,Giannerini, Massimo,Feringa, Ben L.
supporting information, p. 2262 - 2265 (2015/05/13)
The palladium-catalyzed direct cross-coupling of a range of organic chlorides and bromides with the bifunctional C(sp3)-(trimethylsilyl)methyllithium reagent is reported. The use of Pd-PEPPSI-IPent as the catalyst allows for the preparation of structurally diverse and synthetically versatile benzyl- and allylsilanes in high yields under mild conditions (room temperature) with short reaction times.
