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2,3,4-Trifluoroaniline

1.1

IDENTIFICATION OF THE SUBSTANCE/MIXTURE AND OF THE COMPANY/UNDERTAKING

Product identifiers

Product name

Product Number

Brand

Index-No.

CAS-No.

2,3,4-Trifluoroaniline

304352

Anonymous

612-187-00-1

3862-73-5

1.2

Relevant identified uses of the substance or mixture and uses advised against

Identified uses

Laboratory chemicals, Manufacture of substances

2.1

2.2

HAZARDS IDENTIFICATION

Classification of the substance or mixture

Classification according to Regulation (EC) No 1272/2008 [EU-GHS/CLP]

Specific target organ toxicity - repeated exposure (Category 2)

Skin irritation (Category 2)

Serious eye damage (Category 1)

Chronic aquatic toxicity (Category 2)

Acute toxicity, Dermal (Category 4)

Acute toxicity, Oral (Category 4)

Classification according to EU Directives 67/548/EEC or 1999/45/EC

Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. Irritating to

skin. Risk of serious damage to eyes. Harmful in contact with skin and if swallowed. Harmful: danger of

serious damage to health by prolonged exposure if swallowed.

Label elements

Labelling according Regulation (EC) No 1272/2008 [CLP]

Pictogram

Signal word

Hazard statement(s)

H315

H373

H302

H312

Danger

Causes skin irritation.

May cause damage to organs through prolonged or repeated exposure.

Harmful if swallowed.

Harmful in contact with skin.

H318

H411

Precautionary statement(s)

P273

P280

P305 + P351 + P338

Supplemental Hazard

Causes serious eye damage.

Toxic to aquatic life with long lasting effects.

Avoid release to the environment.

Wear protective gloves/ eye protection/ face protection.

IF IN EYES: Rinse cautiously with water for several minutes. Remove

contact lenses, if present and easy to do. Continue rinsing.

none

Statements

According to European Directive 67/548/EEC as amended.

Hazard symbol(s)

R-phrase(s)

R21/22

R38

R41

R48/22

R51/53

Harmful in contact with skin and if swallowed.

Irritating to skin.

Risk of serious damage to eyes.

Harmful: danger of serious damage to health by prolonged exposure if

swallowed.

Toxic to aquatic organisms, may cause long-term adverse effects in the

aquatic environment.

S-phrase(s)

S23

S26

S36/37/39

S61

Do not breathe gas/fumes/vapour/spray.

In case of contact with eyes, rinse immediately with plenty of water and

seek medical advice.

Wear suitable protective clothing, gloves and eye/face protection.

Avoid release to the environment. Refer to special instructions/ Safety

data sheets.

2.3

3.1

Other hazards - none

COMPOSITION/INFORMATION ON INGREDIENTS

Substances

Formula

Molecular Weight

Component

2,3,4-Trifluoroaniline

C6H4F3N

147,1 g/mol

Concentration

CAS-No.

EC-No.

Index-No.

3862-73-5

407-170-9

612-187-00-1

4.1

FIRST AID MEASURES

Description of first aid measures

General advice

Consult a physician. Show this safety data sheet to the doctor in attendance.

If inhaled

If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.

In case of skin contact

Wash off with soap and plenty of water. Consult a physician.

In case of eye contact

Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.

If swallowed

Do NOT induce vomiting. Never give anything by mouth to an unconscious person. Rinse mouth with

water. Consult a physician.

4.2

4.3

5.1

5.2

5.3

5.4

6.1

6.2

6.3

6.4

7.1

7.2

7.3

Most important symptoms and effects, both acute and delayed

Absorption into the body leads to the formation of methemoglobin which in sufficient concentration causes

cyanosis. Onset may be delayed 2 to 4 hours or longer., To the best of our knowledge, the chemical,

physical, and toxicological properties have not been thoroughly investigated.

Indication of any immediate medical attention and special treatment needed

no data available

FIREFIGHTING MEASURES

Extinguishing media

Suitable extinguishing media

Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.

Special hazards arising from the substance or mixture

Carbon oxides, nitrogen oxides (NOx), Hydrogen fluoride

Advice for firefighters

Wear self contained breathing apparatus for fire fighting if necessary.

Further information

Use water spray to cool unopened containers.

ACCIDENTAL RELEASE MEASURES

Personal precautions, protective equipment and emergency procedures

Use personal protective equipment. Avoid breathing vapors, mist or gas. Ensure adequate ventilation.

Remove all sources of ignition. Evacuate personnel to safe areas. Beware of vapours accumulating to

form explosive concentrations. Vapours can accumulate in low areas.

Environmental precautions

Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the

environment must be avoided.

Methods and materials for containment and cleaning up

Contain spillage, and then collect with an electrically protected vacuum cleaner or by wet-brushing and

place in container for disposal according to local regulations (see section 13). Keep in suitable, closed

containers for disposal.

Reference to other sections

For disposal see section 13.

HANDLING AND STORAGE

Precautions for safe handling

Avoid contact with skin and eyes. Avoid inhalation of vapour or mist.

Keep away from sources of ignition - No smoking.Take measures to prevent the build up of electrostatic

charge.

Conditions for safe storage, including any incompatibilities

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Containers which are

opened must be carefully resealed and kept upright to prevent leakage.

Specific end uses

no data available

8.1

8.2

9.1

EXPOSURE CONTROLS/PERSONAL PROTECTION

Control parameters

Components with workplace control parameters

Exposure controls

Appropriate engineering controls

Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and

at the end of workday.

Personal protective equipment

Eye/face protection

Tightly fitting safety goggles. Faceshield (8-inch minimum). Use equipment for eye protection

tested and approved under appropriate government standards such as NIOSH (US) or EN

166(EU).

Skin protection

Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique

(without touching glove's outer surface) to avoid skin contact with this product. Dispose of

contaminated gloves after use in accordance with applicable laws and good laboratory practices.

Wash and dry hands.

The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and

the standard EN 374 derived from it.

Body Protection

Complete suit protecting against chemicals, The type of protective equipment must be selected

according to the concentration and amount of the dangerous substance at the specific workplace.

Respiratory protection

Where risk assessment shows air-purifying respirators are appropriate use a full-face respirator

with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup

to engineering controls. If the respirator is the sole means of protection, use a full-face supplied air

respirator. Use respirators and components tested and approved under appropriate government

standards such as NIOSH (US) or CEN (EU).

PHYSICAL AND CHEMICAL PROPERTIES

Information on basic physical and chemical properties

Appearance

Odour

Odour Threshold

Melting point/freezing

point

Initial boiling point and

boiling range

Flash point

Evaporation rate

Form: clear, liquid

Colour: light yellow

no data available

92 °C at 64 hPa - lit.

68 °C - closed cup

no data available

Flammability (solid, gas) no data available

Upper/lower

flammability or

explosive limits

Vapour pressure

Vapour density

no data available

m) Relative density

1,393 g/mL at 25 °C

Water solubility

Partition coefficient: n-

octanol/water

Autoignition

temperature

Decomposition

temperature

Viscosity

Explosive properties

Oxidizing properties

no data available

9.2

10.

10.1

10.2

10.3

10.4

10.5

10.6

11.

11.1

Other safety information

no data available

STABILITY AND REACTIVITY

Reactivity

no data available

Chemical stability

no data available

Possibility of hazardous reactions

no data available

Conditions to avoid

Heat, flames and sparks.

Incompatible materials

Strong oxidizing agents, Strong acids, Acid chlorides, Acid anhydrides

Hazardous decomposition products

Other decomposition products - no data available

TOXICOLOGICAL INFORMATION

Information on toxicological effects

Acute toxicity

LD50 Oral - rat - 699 mg/kg

Remarks: Behavioral:Somnolence (general depressed activity). Cyanosis Gastrointestinal:Changes in

structure or function of salivary glands.

Skin corrosion/irritation

Skin - rabbit - Skin irritation

Serious eye damage/eye irritation

no data available

Respiratory or skin sensitization

no data available

Germ cell mutagenicity

no data available

Carcinogenicity

IARC:

No component of this product present at levels greater than or equal to 0.1% is identified as

probable, possible or confirmed human carcinogen by IARC.

Reproductive toxicity

no data available

Specific target organ toxicity - single exposure

no data available

Specific target organ toxicity - repeated exposure

no data available

Aspiration hazard

no data available

Potential health effects

Inhalation

Ingestion

Skin

Eyes

May be harmful if inhaled. Causes respiratory tract irritation.

Harmful if swallowed.

May be harmful if absorbed through skin. Causes skin irritation.

Causes eye burns.

Signs and Symptoms of Exposure

Absorption into the body leads to the formation of methemoglobin which in sufficient concentration causes

cyanosis. Onset may be delayed 2 to 4 hours or longer., To the best of our knowledge, the chemical,

physical, and toxicological properties have not been thoroughly investigated.

Additional Information

RTECS: CY1211500

12.

12.1

12.2

12.3

12.4

12.5

12.6

13.

13.1

14.

14.1

ECOLOGICAL INFORMATION

Toxicity

no data available

Persistence and degradability

no data available

Bioaccumulative potential

no data available

Mobility in soil

no data available

Results of PBT and vPvB assessment

no data available

Other adverse effects

Toxic to aquatic life.

Avoid release to the environment.

DISPOSAL CONSIDERATIONS

Waste treatment methods

Product

This combustible material may be burned in a chemical incinerator equipped with an afterburner and

scrubber. Offer surplus and non-recyclable solutions to a licensed disposal company.

Contaminated packaging

Dispose of as unused product.

TRANSPORT INFORMATION

UN number

14.2

ADR/RID: 3082

UN proper shipping name

IMDG: 3082

IATA: 3082

ADR/RID:

IMDG:

IATA:

ENVIRONMENTALLY HAZARDOUS SUBSTANCE, LIQUID, N.O.S. (2,3,4-Trifluoroaniline)

Environmentally hazardous substance, liquid, n.o.s. (2,3,4-Trifluoroaniline)

14.3

Transport hazard class(es)

ADR/RID: 9

IMDG: 9

IATA: 9

14.4

Packaging group

14.5

14.6

ADR/RID: III

Environmental hazards

ADR/RID: yes

Special precautions for user

IMDG: III

IMDG Marine pollutant: no

IATA: III

IATA: yes

Further information

EHS-Mark required (ADR 2.2.9.1.10, IMDG code 2.10.3) for single packagings and combination

packagings containing inner packagings with Dangerous Goods > 5L for liquids or > 5kg for solids.

15.

15.1

15.2

16.

REGULATORY INFORMATION

This safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006.

Safety, health and environmental regulations/legislation specific for the substance or mixture

no data available

Chemical Safety Assessment

no data available

OTHER INFORMATION

Further information

The above information is believed to be correct but does not purport to be all inclusive and
shall be used only as a guide. The information this document is based on the resent state
of our knowledge and is applicable to the product with regard to appropriate safety precautions.
It does not represent any guarantee of the properties of the product. Lookchem shall not be
held liable for any damage resulting from handling or from contact with the above product.
See reverse side of invoice or packing slip for additional terms and conditions of sale.

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