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Section 1 - Chemical Product and Company Identification |
MSDS Name: 4-Chlorobenzyl cyanide, 98+%
Catalog Numbers:
AC108810000, AC108810050, AC108811000, AC108812500, AC108815000
Synonyms:
(4-Chlorophenyl)acetonitrile; PCCN; p-Chlorophenylacetonitrile.
Company Identification:
Acros Organics N.V.
One Reagent Lane
Fair Lawn, NJ 07410
For information in North America, call: 800-ACROS-01
For emergencies in the US, call CHEMTREC: 800-424-9300
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Section 2 - Composition, Information on Ingredients
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| CAS# |
Chemical Name |
Percent |
EINECS/ELINCS |
| 140-53-4 |
4-Chlorobenzyl cyanide |
> 98 | 205-418-9 |
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Section 3 - Hazards Identification
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EMERGENCY OVERVIEW
Appearance: colorless to yellow crystalline powder.
Danger! May be fatal if swallowed. Harmful if
absorbed through skin or if inhaled. May cause eye and skin
irritation. May cause respiratory tract irritation.
Target Organs: Central nervous system, lungs,
eyes, skin.
Potential Health Effects
Eye:
May cause eye irritation.
Skin:
May cause skin irritation. Harmful if absorbed through the skin. May
be metabolized to cyanide which in turn acts by inhibiting cytochrome
oxidase impairing cellular respiration. Most nitrile compounds are
well absorbed through intact skin, and may cause delayed onset of
symptoms following exposure by this route.
Ingestion:
May cause irritation of the digestive tract. Poison by ingestion.
Metabolism may release cyanide, which may result in headache,
dizziness, weakness, collapse, unconsciousness and possible death.
Inhalation:
Harmful if inhaled. May cause respiratory tract irritation.
Inhalation may result in symptoms similar to cyanide poisoning which
include tachypnea, hyperpnea (abnormally rapid or deep breathing),
and dyspnea (labored breathing) followed rapidly by respiratory
depression. Pulmonary edema may occur.
Chronic:
May be metabolized to cyanide which in turn acts by inhibiting
cytochrome oxidase impairing cellular respiration. Chronic exposure
to cyanide solutions may lead to the development of a "cyanide" rash,
characterized by itching, and by macular, papular, and vesicular
eruptions, and may be accompanied by secondary infections. Exposure
to small amounts of cyanide compounds over long periods of time is
reported to cause loss of appetite, headache, weakness, nausea,
dizziness, and symptoms of irritation of the upper respiratory tract
and eyes.
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Section 4 - First Aid Measures
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Eyes:
In case of contact, immediately flush eyes with plenty of water for a
t least 15 minutes. Get medical aid.
Skin:
In case of contact, immediately flush skin with plenty of water for
at least 15 minutes while removing contaminated clothing and shoes.
Get medical aid immediately. Wash clothing before reuse.
Ingestion:
If swallowed, do not induce vomiting unless directed to do so by
medical personnel. Never give anything by mouth to an unconscious
person. Get medical aid.
Inhalation:
If inhaled, remove to fresh air. If not breathing, give artificial
respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:
Treat symptomatically and supportively.
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Section 5 - Fire Fighting Measures
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General Information:
As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full
protective gear. During a fire, irritating and highly toxic gases
may be generated by thermal decomposition or combustion. Approach
fire from upwind to avoid hazardous vapors and toxic decomposition
products.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or appropriate foam.
Flash Point: 133 deg C ( 271.40 deg F)
Autoignition Temperature: > 500 deg C (> 932.00 deg F)
Explosion Limits, Lower:Not available.
Upper: Not available.
NFPA Rating:
(estimated) Health: 3; Flammability: 1; Instability: 0
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Section 6 - Accidental Release Measures
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General Information: Use proper personal protective equipment as indicated
in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal
container. Avoid runoff into storm sewers and ditches which lead to
waterways. Clean up spills immediately, observing precautions in the
Protective Equipment section. Avoid generating dusty conditions.
Provide ventilation. Approach spill from upwind.
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Section 7 - Handling and Storage
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Handling:
Wash thoroughly after handling. Remove contaminated clothing and
wash before reuse. Avoid contact with eyes, skin, and clothing. Keep
container tightly closed. Avoid ingestion and inhalation. Use only
with adequate ventilation.
Storage:
Store in a tightly closed container. Store in a cool, dry,
well-ventilated area away from incompatible substances.
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Section 8 - Exposure Controls, Personal Protection
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Engineering Controls:
Facilities storing or utilizing this material should be equipped
with an eyewash facility and a safety shower. Use adequate
ventilation to keep airborne concentrations low.
Exposure Limits
| Chemical Name |
ACGIH |
NIOSH |
OSHA - Final PELs |
| 4-Chlorobenzyl cyanide
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none listed
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none listed
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5 mg/m3 TWA (listed under Cyanide anion).
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OSHA Vacated PELs:
4-Chlorobenzyl cyanide:
No OSHA Vacated PELs are listed for this chemical.
Personal Protective Equipment
Eyes:
Wear appropriate protective eyeglasses or chemical
safety goggles as described by OSHA's eye and face
protection regulations in 29 CFR 1910.133 or European
Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin
exposure.
Clothing:
Wear appropriate protective clothing to prevent skin
exposure.
Respirators:
Follow the OSHA respirator regulations found in 29
CFR 1910.134 or European Standard EN 149. Use a
NIOSH/MSHA or European Standard EN 149 approved
respirator if exposure limits are exceeded or if
irritation or other symptoms are experienced.
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Section 9 - Physical and Chemical Properties
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Physical State: Crystalline powder
Appearance: colorless to yellow
Odor: None reported.
pH: Not available.
Vapor Pressure: Not available.
Vapor Density: Not available.
Evaporation Rate:Not available.
Viscosity: Not available.
Boiling Point: 265 - 267 deg C @ 760 mm Hg
Freezing/Melting Point:29 - 30 deg C
Decomposition Temperature:Not available.
Solubility: Insoluble.
Specific Gravity/Density:Not available.
Molecular Formula:C8H6ClN
Molecular Weight:151.60
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Section 10 - Stability and Reactivity
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Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
Dust generation, temperatures above 40?C.
Incompatibilities with Other Materials:
Strong oxidizing agents, strong reducing agents, strong acids, strong
bases.
Hazardous Decomposition Products:
Hydrogen chloride, hydrogen cyanide, nitrogen oxides, carbon
monoxide, carbon dioxide.
Hazardous Polymerization: Has not been reported.
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Section 11 - Toxicological Information
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RTECS#:
CAS# 140-53-4:
AL8250000
LD50/LC50:
CAS# 140-53-4:
Oral, rat: LD50 =
50 mg/kg;
.
Oral LD50 (rat): 50 mg/kg., Skin LDLo (rabbit): 200 mg/kg.
Carcinogenicity:
CAS# 140-53-4:
Not listed by ACGIH, IARC, NTP, or CA Prop 65.
Epidemiology:
No information available.
Teratogenicity:
No information available.
Reproductive Effects:
No information available.
Mutagenicity:
No information available.
Neurotoxicity:
No information available.
Other Studies:
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Section 12 - Ecological Information
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No information available.
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Section 13 - Disposal Considerations
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Chemical waste generators must determine whether a discarded chemical is classified
as a hazardous waste.
US EPA guidelines for the classification determination are listed in 40 CFR Parts 261.3.
Additionally, waste generators must consult state and local hazardous waste regulations to
ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: None listed.
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Section 14 - Transport Information
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US DOT |
Canada TDG |
| Shipping Name: |
NITRILES, TOXIC, SOLID, N.O.S. |
TOXIC SOLID ORGANIC NOS (4-CHLOROBENZYL CYANIDE) |
| Hazard Class: |
6.1 |
6.1 |
| UN Number: |
UN3439 |
UN2811 |
| Packing Group: |
II |
II |
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Section 15 - Regulatory Information
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US FEDERAL
TSCA
CAS# 140-53-4 is listed on the TSCA inventory.
Health & Safety Reporting List
None of the chemicals are on the Health & Safety Reporting List.
Chemical Test Rules
None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
None of the chemicals in this material have a SNUR under TSCA.
CERCLA Hazardous Substances and corresponding RQs
None of the chemicals in this material have an RQ.
SARA Section 302 Extremely Hazardous Substances
None of the chemicals in this product have a TPQ.
SARA Codes
CAS # 140-53-4: immediate, delayed.
Section 313
No chemicals are reportable under Section 313.
Clean Air Act:
This material does not contain any hazardous air pollutants.
This material does not contain any Class 1 Ozone depletors.
This material does not contain any Class 2 Ozone depletors.
Clean Water Act:
None of the chemicals in this product
are listed as Hazardous Substances under the CWA.
CAS# 140-53-4 is listed as a Priority Pollutant under the Clean Water
Act.
CAS# 140-53-4 is listed as a Toxic Pollutant under the Clean Water
Act.
OSHA:
None of the chemicals in this product
are considered highly hazardous by OSHA.
STATE
CAS# 140-53-4 can be found on the
following state right to know lists: California, (listed as Cyanides,
inorganic salts), New Jersey, (listed as Cyanide anion), New Jersey,
(listed as Cyanides, inorganic salts), Pennsylvania, (listed as
Cyanide anion), Massachusetts, (listed as Cyanide anion).
California Prop 65
California No Significant Risk Level:
None of the chemicals in this product are listed.
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols:
T
Risk Phrases:
R 23/24/25 Toxic by inhalation, in contact with skin and if
swallowed.
R 36/37/38 Irritating to eyes, respiratory system and skin.
Safety Phrases:
S 36/37/39 Wear suitable protective clothing, gloves and eye/face pr
otection.
S 45 In case of accident or if you feel unwell, seek medical advice
immediately (show the label where possible).
S 28B After contact with skin, wash immediately with plenty of water
and soap.
WGK (Water Danger/Protection)
CAS# 140-53-4: No information available.
Canada - DSL/NDSL
CAS# 140-53-4 is listed on Canada's NDSL List.
Canada - WHMIS
This product has a WHMIS classification of D1A, D2B.
This product has been classified in accordance with the hazard
criteria of the Controlled Products Regulations and the MSDS
contains all of the information required by those regulations.
Canadian Ingredient Disclosure List
CAS# 140-53-4 (listed as Cyanides, inorganic salts) is listed on the Canadian Ingredient Disclosure List.
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Section 16 - Additional Information
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MSDS Creation Date: 12/10/1998
Revision #8 Date: 4/27/2007
The information above is believed to be accurate and represents the best
information currently available to us. However, we make no warranty of
merchantability or any other warranty, express or implied, with respect to
such information, and we assume no liability resulting from its use. Users
should make their own investigations to determine the suitability of the
information for their particular purposes. In no event shall Fisher be liable
for any claims, losses, or damages of any third party or for lost profits
or any special, indirect, incidental, consequential or exemplary
damages, howsoever arising, even if Fisher has been advised of
the possibility of such damages.
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