Nicotinamide,
N-(3-(4-(p-fluorophenyl)-1-piperazinyl)-1-methylpropy
l)-

CAS  

 27367-90-4

SYNONYMS  

 * N-(3-(4-(p-Fluorophenyl)-1-piperazinyl)-1-methylpropyl)nicotinamide
*   N-(3-(4-(4-Fluorophenyl)-1-piperazinyl)-1-methylpropyl)-3-pyridinecarbox
amide
* Niaprazine
* Nopron
* 3-Pyridinecarboxamide,
N-(3-(4-(4-fluorophenyl)-1-piperazinyl)-1-methylpropyl)-

                     *** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : QS4476100
CHEMICAL NAME           : Nicotinamide,
                          N-(3-(4-(p-fluorophenyl)-1-piperazinyl)-1-methylpropy
                          l)-
CAS REGISTRY NUMBER     : 27367-90-4
BEILSTEIN REFERENCE NO. : 0844157
REFERENCE               : 5-23-01-00362 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C20-H25-F-N4-O
MOLECULAR WEIGHT        : 356.49
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * N-(3-(4-(p-Fluorophenyl)-1-piperazinyl)-1-methylpropyl)nicotinamide
   *   N-(3-(4-(4-Fluorophenyl)-1-piperazinyl)-1-methylpropyl)-3-pyridinecarbox
     amide
   * Niaprazine
   * Nopron
   * 3-Pyridinecarboxamide,  
   N-(3-(4-(4-fluorophenyl)-1-piperazinyl)-1-methylpropyl)-
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 890 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GWXXBX German Offenlegungsschrift Patent Document.  (U.S. Patent and
   Trademark Office, Foreign Patents, Washington, DC 20231)
   Volume(issue)/page/year: #1957371
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 145 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GWXXBX German Offenlegungsschrift Patent Document.  (U.S. Patent and
   Trademark Office, Foreign Patents, Washington, DC 20231)
   Volume(issue)/page/year: #1957371
 
                            *** END OF RECORD ***