Heptanoic acid,2-[4-[3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl]-1-piperazinyl]ethylester

MSDS

 Heptanoic acid,
2-(4-(3-(2-(trifluoromethyl)phenothiazin-10-yl)propyl
)- 1-piperazinyl)ethyl ester

CAS

 2746-81-8

SYNONYMS

 * Eutimox
* Fluphenazine enantate
* Fluphenazine enanthate
* Moditen enanthate
* Moditen-retard
* OF
* Prolixin enanthate
* SQ 16,114
* 4-(3-(2-Trifluoromethyl-10-phenothiazinyl)propyl)-1-piperazineethanol
enanthate
*   2-((4-(3-(2-(Trifluoromethyl)phenothiazin-10-yl)propyl)-1-piperazinyl))e
thyl heptanoate

Catalog of Chemical Suppliers, Buyers, Custom Synthesis Companies And Equipment Manufacturers
[ Heptanoic acid,2-(4-(3-(2-(trifluoromethyl)phenothiazin-10-yl)propyl)- 1-piperazinyl)ethyl ester 2746-81-8 ]

                     *** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : MJ2450000
CHEMICAL NAME           : Heptanoic acid,
                          2-(4-(3-(2-(trifluoromethyl)phenothiazin-10-yl)propyl
                          )- 1-piperazinyl)ethyl ester
CAS REGISTRY NUMBER     : 2746-81-8
BEILSTEIN REFERENCE NO. : 0598595
LAST UPDATED            : 199612
DATA ITEMS CITED        : 7
MOLECULAR FORMULA       : C29-H38-F3-N3-O2-S
MOLECULAR WEIGHT        : 549.76
WISWESSER LINE NOTATION : T C666 BN ISJ EXFFF B3- AT6N DNTJ D2OV6
COMPOUND DESCRIPTOR     : Drug
                          Human
SYNONYMS/TRADE NAMES :
   * Eutimox
   * Fluphenazine enantate
   * Fluphenazine enanthate
   * Moditen enanthate
   * Moditen-retard
   * OF
   * Prolixin enanthate
   * SQ 16,114
   * 4-(3-(2-Trifluoromethyl-10-phenothiazinyl)propyl)-1-piperazineethanol  
   enanthate
   *   2-((4-(3-(2-(Trifluoromethyl)phenothiazin-10-yl)propyl)-1-piperazinyl))e
     thyl heptanoate
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Human
DOSE/DURATION           : 357 ug/kg
TOXIC EFFECTS :
   Behavioral - muscle weakness
REFERENCE :
   AJPSAO American Journal of Psychiatry.  (American Psychiatric Assoc.,
   Circulation Dept., 1400 K St., NW, Washington, DC 20005)  V.78-    1921-
   Volume(issue)/page/year: 119,779,1963
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intramuscular
SPECIES OBSERVED        : Human
DOSE/DURATION           : 1633 ug/kg
TOXIC EFFECTS :
   Musculoskeletal - other changes
REFERENCE :
   BMJOAE British Medical Journal.  (British Medical Assoc., BMA House,
   Tavistock Sq., London WC1H 9JR, UK)  V.1-    1857- Volume(issue)/page/year:
   2,1071,1966
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 300 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NIIRDN Drugs in Japan (Ethical Drugs).  (Yakugyo Jiho Co., Ltd., Tokyo,
   Japan)  Volume(issue)/page/year: 6,701,1982
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 50 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NIIRDN Drugs in Japan (Ethical Drugs).  (Yakugyo Jiho Co., Ltd., Tokyo,
   Japan)  Volume(issue)/page/year: 6,701,1982
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 56 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems
   Laboratory, NIOSH Exchange Chemicals.  (Aberdeen Proving Ground, MD 21010)
   Volume(issue)/page/year: NX#03337
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intramuscular
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 17200 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NIIRDN Drugs in Japan (Ethical Drugs).  (Yakugyo Jiho Co., Ltd., Tokyo,
   Japan)  Volume(issue)/page/year: 6,701,1982

                              *** REVIEWS ***
 
   TOXICOLOGY REVIEW
   ABPYBL Advances in Biochemical Psychopharmacology.  (Raven Press, 1185 Ave.
   of the Americas, New York, NY 10036)  V.1-    1969- Volume(issue)/page/year:
   9,301,1974

 
                            *** END OF RECORD ***

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