Harmine, hydrochloride

CAS  

 343-27-1

SYNONYMS  

 * Harmine monohydrochloride
* 7-Methoxy-1-methyl-9H-pyrido(3,4-b)indole hydrochloride
* 9H-Pyrido(3,4-b)indole, 7-methoxy-1-methyl-, monohydrochloride

                     *** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : MG9450000
CHEMICAL NAME           : Harmine, hydrochloride
CAS REGISTRY NUMBER     : 343-27-1
LAST UPDATED            : 199709
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C13-H12-N2-O.Cl-H
MOLECULAR WEIGHT        : 248.73
WISWESSER LINE NOTATION : T B656 EN HMJ F1 KO1 &GH
COMPOUND DESCRIPTOR     : Drug
                          Mutagen
SYNONYMS/TRADE NAMES :
   * Harmine monohydrochloride
   * 7-Methoxy-1-methyl-9H-pyrido(3,4-b)indole hydrochloride
   * 9H-Pyrido(3,4-b)indole, 7-methoxy-1-methyl-, monohydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 38 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 79,127,1943

                          *** STATUS IN U.S. ***
 
   EPA GENETOX PROGRAM 1988, Positive: Histidine reversion-Ames test

 
                            *** END OF RECORD ***