1H,10H-Pyrrolo[1,2-c]purine-10,10-diol,2,6-diamino-4-[[(aminocarbonyl)oxy]methyl]-3a,4,8,9-tetrahydro-, hydrochloride(1:2), (3aS,4R,10aS)-

MSDS

 1H,10H-Pyrrolo(1,2-C)purine-10,10-diol,
3a,4,8,9-tetrahydro-2,6-diamino-4-(((aminocarbonyl)
oxy)methyl)-, dihydrochloride,
(3aS-(3a-alpha,4-alpha,10aR*))-

CAS

 35554-08-6

SYNONYMS

 * Biclorhidrato de saxotoxina
* Clam poison dihydrochloride
* Gonyaulax catenella poison dihydrochloride
* Gonyaulax toxic dihydrochloride
* Mussel poison dihydrochloride
* Paralytic shellfish poison dihydrochloride
* Saxitoxin dihydrochloride
* Saxitoxin hydrochloride
* STX dihydrochloride

Catalog of Chemical Suppliers, Buyers, Custom Synthesis Companies And Equipment Manufacturers
[ 1H,10H-Pyrrolo(1,2-C)purine-10,10-diol,3a,4,8,9-tetrahydro-2,6-diamino-4-(((aminocarbonyl)oxy)methyl)-, dihydrochloride,(3aS-(3a-alpha,4-alpha,10aR*))- 35554-08-6 ]

                     *** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UY8708600
CHEMICAL NAME           : 1H,10H-Pyrrolo(1,2-C)purine-10,10-diol,
                          3a,4,8,9-tetrahydro-2,6-diamino-4-(((aminocarbonyl)
                          oxy)methyl)-, dihydrochloride,
                          (3aS-(3a-alpha,4-alpha,10aR*))-
CAS REGISTRY NUMBER     : 35554-08-6
LAST UPDATED            : 199806
DATA ITEMS CITED        : 7
MOLECULAR FORMULA       : C10-H17-N7-O4.2Cl-H
MOLECULAR WEIGHT        : 372.26
WISWESSER LINE NOTATION : T565 1A L AXMYM GMYN EH&TTJ CUM F1OVZ HUM LQ LQ &GH 2
COMPOUND DESCRIPTOR     : Drug
                          Natural Product
SYNONYMS/TRADE NAMES :
   * Biclorhidrato de saxotoxina
   * Clam poison dihydrochloride
   * Gonyaulax catenella poison dihydrochloride
   * Gonyaulax toxic dihydrochloride
   * Mussel poison dihydrochloride
   * Paralytic shellfish poison dihydrochloride
   * Saxitoxin dihydrochloride
   * Saxitoxin hydrochloride
   * STX dihydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 85 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AFMMBW Archivos de la Facultad de Medicina de Madrid.  (Madrid, Spain)
   V.1-40, 1961-81.  Volume(issue)/page/year: 8,151,1965
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 263 ug/kg
TOXIC EFFECTS :
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   2,607,1960
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 8 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   2,607,1960
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 3400 ng/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   2,607,1960
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 3 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   14FHAR "Venomous and Poisonous Animals and Noxious Plants of the Pacific
   Region," Keegan, H.L., and W.V. Macfarlane, eds., New York, Pergamon Press
   Inc., 1963  Volume(issue)/page/year: -,75,1963
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Amphibian - frog
DOSE/DURATION           : 75 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TOXIA6 Toxicon.  (Pergamon Press Ltd., Headington Hill Hall, Oxford OX3 OBW,
   UK)  V.1-    1962-  Volume(issue)/page/year: 5,25,1967
 
TYPE OF TEST            : LD - Lethal dose
ROUTE OF EXPOSURE       : Parenteral
SPECIES OBSERVED        : Mammal - domestic
DOSE/DURATION           : >126 ng/kg
TOXIC EFFECTS :
   Behavioral - general anesthetic
REFERENCE :
   USXXAM United States Patent Document.  (U.S. Patent Office, Box 9,
   Washington, DC 20231)  Volume(issue)/page/year: #3892847
 
                            *** END OF RECORD ***

;