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Prosta-5,13-dien-1-oicacid, 9,11-dihydroxy-15-oxo-, (5Z,9a,11a,13E)-

MSDS: 15-keto Prostaglandin F2.alpha. 3/13/02 2:39 PM

MATERIAL SAFETY DATA SHEET

SECTION 1. Chemical Product and Company Identification
15-keto Prostaglandin F2.alpha.

Product Code: 16720 , Reference #: PGT
Product Name: 15-keto Prostaglandin F2.alpha.
CAS Number: 35850-13-6
Chemical Family: Prostaglandins
Synonyms
9.alpha.,11.alpha.-dihydroxy-15-oxo-prosta-5Z,13E-dien-1-oic acid
Manufacturer Name and Address: Telephone Numbers: Dates:
Cayman Chemical Company Cayman Chemical Company (800)364-9897 Date Entered: 06/27/1996
1180 E. Ellsworth Rd. Revision: 02/28/2002
Ann Arbor, MI. 48108 Cayman Chemical Company (734)971-3335 Printed: 03/13/2002

SECTION 2. Composition/Information on Ingredients
15-keto Prostaglandin F2.alpha.

Hazardous Components (Specific Chemical Identity/Common Name) CAS # Percentage
15-keto Prostaglandin F2.alpha. 35850-13-6 1.0
Methyl acetate {Methyl ester of acetic acid} 79-20-9 99.0

SECTION 3. Hazards Identification
15-keto Prostaglandin F2.alpha.

Emergency Overview
Route(s) of Entry: Inhalation? Yes , Skin? Yes , Eyes? Yes , Ingestion? Yes , Other: Injection
Potential Health Effects (Acute and Chronic)
Contact may cause skin or eye irritation.
Material is irritating to the mucous membranes and upper respiratory tract.
May be harmful by inhalation, ingestion, or skin absorption.
Repeated exposure may cause skin dryness or cracking.
Vapors may cause drowsiness and dizziness.
The toxicological properties of this compound have not been fully evaluated.
Carcinogeniticy: NTP? No , IARC Monographs? No , OSHA Regulated? No
Carcinogenicity/Other Information
Signs and Symptoms Of Exposure

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Irritating to the skin, eyes, nose, throat, and respiratory tract.

SECTION 4. First Aid Measures
15-keto Prostaglandin F2.alpha.

Emergency and First Aid Procedures
If inhaled remove to fresh air. If not breathing, give artificial respiration or give oxygen by trained personnel. Get immediate
medical attention.
If swallowed, wash out mouth with water provided person is conscious. Never give anything by mouth to an unconscious
person. Get medical attention.
In case of contact with eyes, hold eyelids apart and flush eyes with plenty of water. After initial flushings, remove any contact
lenses and continue flushing for at least 15 minutes. Have eyes examined and tested by medical personnel.
In case of skin contact, immediately wash skin with soap and plenty of water. Remove contaminated clothing. Get medical
attention if symptoms occur. Wash clothing before reuse.
Note to Physician

Medical Conditions Generally Aggravated By Exposure

SECTION 5. Fire Fighting Measures
15-keto Prostaglandin F2.alpha.

Flash Pt: 15.0 F Method Used:
Explosive Limits: LEL: UEL:
Autoignition Pt: 936.0 F Extinguishing Media
Use alcohol foam, carbon dioxide, or water spray when fighting fires involving this material.
Fire Fighting Instructions
As in any fire, wear self-contained breathing apparatus pressure-demand (MSHA/NIOSH approved or equivalent), and full
protective gear to prevent contact with skin and eyes.
Note: Flammable as diluted in methyl acetate.
Flammable Properties and Hazards
Can release vapors that form explosive mixtures at temperatures at or above the flash point.
Emits toxic fumes under fire conditions.
Flammable liquid.
Vapors can travel to a source of ignition and flash back.
Hazardous Combustion Products
carbon dioxide
carbon monoxide

SECTION 6. Accidental Release Measures
15-keto Prostaglandin F2.alpha.

Steps To Be Taken In Case Material Is Released Or Spilled
Absorb spill with inert material (e.g. dry sand or earth), then place in a chemical waste container.
After removal, ventilate contaminated area and flush thoroughly with water.

SECTION 7. Handling and Storage
15-keto Prostaglandin F2.alpha.

Hazard Label Information:

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Avoid contact with skin and eyes. Do not reuse this container.
Use with adequate ventilation. Wash thoroughly after handling.
Precautions To Be Taken in Handling
Avoid contact with eyes, skin, and clothing.
Do not reuse this container.
Keep away from sources of ignition.
Pregnant females should avoid exposure to this compound.
Use with adequate ventilation.
Wash thoroughly after handling.
Precautions To Be Taken in Storing
Store at correct temperature.
Other Precautions
Work/Hygienic/Maintenance Practices
Do not take internally.
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower.
Wash thoroughly after handling.

SECTION 8. Exposure Controls/Personal Protection
15-keto Prostaglandin F2.alpha.

Protective Equipment Summary - Hazard Label Information
Eye wash station in work area Lab coat Latex disposable gloves
Safety glasses Safety shower in work area Vent Hood
Respiratory Equipment (Specify Type)

Eye Protection
Safety glasses
Protective Gloves
Latex disposable gloves
Other Protective Clothing
Lab coat
Engineering Controls (Ventilation etc.)
Good general ventilation should be sufficient to control airborne levels.

SECTION 9. Physical and Chemical Properties
15-keto Prostaglandin F2.alpha.

Physical States: [ ] Gas , [ X ] Liquid , [ ] Solid
Boiling Point: NE or NA
Melting Point:
Specific Gravity (Water = 1): NE or NA
Vapor Pressure (vs. Air or mm Hg): NE or NA
Vapor Density (vs. Air = 1): NE or NA
Evaporation Rate (vs Butyl Acetate=1): NE or NA
Solubility in Water: *10 mg/ml at 25.0 C
Other Solubility Notes: *PBS pH 7.2, sol. in DMF, DMSO & EtOH
Percent Volatile: NE or NA
Molecular Formula: C20H32O5
Molecular Weight: 352.50
pH:
Appearance and Odor
A clear, colorless solution

SECTION 10. Stability and Reactivity

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15-keto Prostaglandin F2.alpha.

Stability: Unstable [ ] Stable [ X ]
Conditions To Avoid - Instability

Incompatibility - Materials To Avoid
Hazardous Decomposition Or Byproducts
Hazardous Polymerization: Will occur [ ] Will not occur [ X ]
Conditions To Avoid - Hazardous Polymerization

SECTION 11. Toxicological Information
15-keto Prostaglandin F2.alpha.

The toxicological effects of this compound have not been thoroughly studied.
Chronic Toxicological Effects

SECTION 12. Ecological Information
15-keto Prostaglandin F2.alpha.

Data not yet available.

SECTION 13. Disposal Considerations
15-keto Prostaglandin F2.alpha.

Waste Disposal Method
Dispose in accordance with local, state and federal regulations.

SECTION 14. Transport Information
15-keto Prostaglandin F2.alpha.

DOT Proper Shipping Name
Additional Transport Information
Transport in accordance with local, state, and federal regulations.

SECTION 15. Regulatory Information
15-keto Prostaglandin F2.alpha.

The data given here is based on current knowledge and experience. The purpose of this safety data sheet is to describe the
products in terms of their safety requirements. The data does not signify any guarantee with regard to the product's properties.
file:///CAYMAN.SYS/SHARE/PDFs/MSDSs/16720m.htm MSDS: 15-keto Prostaglandin F2.alpha. 3/13/02 2:39 PM

SECTION 16. Other Information
15-keto Prostaglandin F2.alpha.

For research use only, not for human or veterinary clinical use.
DISCLAIMER: This information is believed to be accurate and represents the best information currently available to us.
However, we make no warranty of merchantability or any other warranty, express or implied, with respect to such information,
and we assume no liability resulting from its use. Users should make their own investigations to determine the suitability of the
information for their particular purposes.

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