*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : KL9400000
CHEMICAL NAME : Ethanol, 2,2'-nitroiminodi-, dinitrate (ester)
CAS REGISTRY NUMBER : 4185-47-1
BEILSTEIN REFERENCE NO. : 1803252
REFERENCE : 4-04-00-03414 (Beilstein Handbook Reference)
LAST UPDATED : 199612
DATA ITEMS CITED : 5
MOLECULAR FORMULA : C4-H8-N4-O8
MOLECULAR WEIGHT : 240.16
WISWESSER LINE NOTATION : WNO2NNW2ONW
COMPOUND DESCRIPTOR : Drug
SYNONYMS/TRADE NAMES :
* Diethanolnitramine dinitrate
* Diethanol-N-nitramine dinitrate
* DINA
* 2,2'-Dinitrato-N-nitrodiethylamine
* sym-Dinitroxydiethylnitramine
* Ethanol, 2,2'-(nitroimino)bis-, dinitrate (ester)
* Nitrodiethanolamine dinitrate
* N-Nitrodiethanolamine dinitrate
* 2,2'-Nitroiminobis(ethylnitrate)
* 2,2'-(Nitroimino)bisethanol dinitrate (ester)
* 2,2'-Nitroiminodiethanol nitrate
* 2,2'-(Nitroimino)ethanol dinitrate
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 3360 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
KHZDAN Khigiena i Zdraveopazvane. Hygiene and Sanitation. (Hemus, Blvd.
Russki 6, Sofia, Bulgaria) V.9- 1966- Volume(issue)/page/year: 9,50,1966
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 180 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity)
Behavioral - convulsions or effect on seizure threshold
REFERENCE :
PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation
of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1-
1967- Volume(issue)/page/year: 10,1504,1976
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - guinea pig
DOSE/DURATION : >200 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
THERAP Therapie. (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris,
France) V.1- 1946- Volume(issue)/page/year: 8,565,1953
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - guinea pig
DOSE/DURATION : 25 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
THERAP Therapie. (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris,
France) V.1- 1946- Volume(issue)/page/year: 8,565,1953
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intramuscular
SPECIES OBSERVED : Rodent - guinea pig
DOSE/DURATION : >400 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
THERAP Therapie. (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris,
France) V.1- 1946- Volume(issue)/page/year: 8,565,1953
*** END OF RECORD ***
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