Butanedioic acid,1-(7-chloro-2,3-dihydro-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl) ester

MSDS

 Succinic acid, monoester with
7-chloro-1,3-dihydro-3-hydroxy-5-phenyl-2H-1,4-benzod
iazepin- 2-one

CAS

 4700-56-5

SYNONYMS

 * Butanedioic acid,
mono(7-chloro-2,3-dihydro-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl) ester
* 7-Chloro-1,3-dihydro-3-hemisuccinyloxy-2H-1,4-benzodiazepin-2-one
* Empracil
* Nulans
* Oxazepam succinate
* SAS 538

Catalog of Chemical Suppliers, Buyers, Custom Synthesis Companies And Equipment Manufacturers
[ Succinic acid, monoester with7-chloro-1,3-dihydro-3-hydroxy-5-phenyl-2H-1,4-benzodiazepin- 2-one 4700-56-5 ]

                     *** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : WM9645000
CHEMICAL NAME           : Succinic acid, monoester with
                          7-chloro-1,3-dihydro-3-hydroxy-5-phenyl-2H-1,4-benzod
                          iazepin- 2-one
CAS REGISTRY NUMBER     : 4700-56-5
BEILSTEIN REFERENCE NO. : 0769233
LAST UPDATED            : 199712
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C19-H15-Cl-N2-O5
MOLECULAR WEIGHT        : 386.81
WISWESSER LINE NOTATION : T67 GMV JN IHJ CG IOV2VQ KR
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Butanedioic acid,  
   mono(7-chloro-2,3-dihydro-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl) ester
   * 7-Chloro-1,3-dihydro-3-hemisuccinyloxy-2H-1,4-benzodiazepin-2-one
   * Empracil
   * Nulans
   * Oxazepam succinate
   * SAS 538
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1148 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Vascular - BP lowering not characterized in autonomic section
REFERENCE :
   FRPPAO Farmaco, Edizione Pratica. (Casella Postale 227, 27100 Pavia, Italy)
   V.8-43    1953-88 For publisher information, see FRMCE8
   Volume(issue)/page/year: 22,506,1967
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 375 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Vascular - BP lowering not characterized in autonomic section
REFERENCE :
   FRPPAO Farmaco, Edizione Pratica. (Casella Postale 227, 27100 Pavia, Italy)
   V.8-43    1953-88 For publisher information, see FRMCE8
   Volume(issue)/page/year: 22,506,1967
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 285 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Vascular - BP lowering not characterized in autonomic section
REFERENCE :
   FRPPAO Farmaco, Edizione Pratica. (Casella Postale 227, 27100 Pavia, Italy)
   V.8-43    1953-88 For publisher information, see FRMCE8
   Volume(issue)/page/year: 22,506,1967
 
                            *** END OF RECORD ***

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