*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : CE1057950
CHEMICAL NAME : 6a-alpha-Aporphin-11-ol, 1,2,10-trimethoxy-
CAS REGISTRY NUMBER : 475-67-2
BEILSTEIN REFERENCE NO. : 0094792
REFERENCE : 5-21-06-00132 (Beilstein Handbook Reference)
LAST UPDATED : 199612
DATA ITEMS CITED : 4
MOLECULAR FORMULA : C20-H23-N-O4
MOLECULAR WEIGHT : 341.44
COMPOUND DESCRIPTOR : Drug
SYNONYMS/TRADE NAMES :
* Artabotrin
* Artabotrine
* 4H-Dibenzo(de,g)quinolin-11-ol,
5,6,6a,7-tetrahydro-1,2,10-trimethoxy-6-methyl-, (S)-
* Isocorydine
* (+)-Isocorydine
* d-Isocorydine
* L-(+)-Isocorydine
* S-(+)-Isocorydine
* Luteanin
* Luteanine
* Luteanine (aporphine)
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 10900 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AUPMAF Acta Universitatis Palackianae Olomucensis, Facultatis Medicae.
(Statni Pedagogicke Nakladatelstvi, Ostrovni 30, 1 Nove Mesto, 113 01 Prague
1, Czechoslovakia) V.24- 1961- Volume(issue)/page/year: 61,213,1972
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 104 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CTYAD8 Zhongcaoyao. Chinese Traditional and Herbal Medicine. (China
International Book Trading Corp., POB 2820, Beijing, Peop. Rep. China) V.11-
1980- Volume(issue)/page/year: 12,402,1981
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 52 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FATOAO Farmakologiya i Toksikologiya (Moscow). For English translation, see
PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2-
1939- Volume(issue)/page/year: 31,44,1968
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 56 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CTYAD8 Zhongcaoyao. Chinese Traditional and Herbal Medicine. (China
International Book Trading Corp., POB 2820, Beijing, Peop. Rep. China) V.11-
1980- Volume(issue)/page/year: 12,402,1981
*** END OF RECORD ***
|