*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : RV0450000
CHEMICAL NAME : Paraffin waxes and hydrocarbon waxes, chlorinated
CAS REGISTRY NUMBER : 63449-39-8
LAST UPDATED : 199710
DATA ITEMS CITED : 14
COMPOUND DESCRIPTOR : Primary Irritant
SYNONYMS/TRADE NAMES :
* Cerechlor 54
* Cereclor
* Cereclor 30
* Cereclor 42
* Cereclor 48
* Cereclor 52
* Cereclor 54
* Cereclor 70
* Cereclor 51L
* Cereclor 56L
* Cereclor 63L
* Cereclor 65L
* Cereclor 70L
* Cereclor 50LV
* Cereclor S 42
* Cereclor S52
* Cereclor S70
* Chlorcosane
* Chlorez 700
* Chlorez 700HMP
* Chlorinated paraffins
* Chloroparaffine 40G
* Chlorowax
* Chlorowax 40
* Chlorowax 50
* Chlorowax 70
* Chlorowax 500C
* Chlorowax 70S
* Chlorowax S 70
* Clorafin
* Crechlor S 45
* Flexchlor
* NCI-C53587
* Paroil chlorez
* Unichlor
* Unichlor 50
*** HEALTH HAZARD DATA ***
** SKIN/EYE IRRITATION DATA **
TYPE OF TEST : Standard Draize test
ROUTE OF EXPOSURE : Administration onto the skin
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 100 mg/24H
REACTION SEVERITY : Mild
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E.
First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year:
54,514,1980
TYPE OF TEST : Standard Draize test
ROUTE OF EXPOSURE : Administration into the eye
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 100 mg
REACTION SEVERITY : Mild
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E.
First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year:
54,514,1980
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : >21500 uL/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
37ASAA "Kirk-Othmer Encyclopedia of Chemical Technology," 3rd ed., Grayson,
M., and D. Eckroth, eds., New York, John Wiley & Sons, Inc., 1978
Volume(issue)/page/year: 5,786,1979
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Administration onto the skin
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : >10 mL/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
37ASAA "Kirk-Othmer Encyclopedia of Chemical Technology," 3rd ed., Grayson,
M., and D. Eckroth, eds., New York, John Wiley & Sons, Inc., 1978
Volume(issue)/page/year: 5,786,1979
** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 27 mg/kg/90D-C
TOXIC EFFECTS :
Liver - changes in liver weight
Kidney, Ureter, Bladder - changes in bladder weight
Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E.
First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year:
54,514,1980
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 14 gm/kg/14D-I
TOXIC EFFECTS :
Liver - changes in liver weight
Endocrine - other changes
Biochemical - Effect on specific coenzyme - CoA
REFERENCE :
TXCYAC Toxicology. (Elsevier Scientific Pub. Ireland, Ltd., POB 85,
Limerick, Ireland) V.1- 1973- Volume(issue)/page/year: 77,81,1993
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 3500 mg/kg/14D-I
TOXIC EFFECTS :
Liver - changes in liver weight
Biochemical - Effect on specific coenzyme - CoA
REFERENCE :
TXCYAC Toxicology. (Elsevier Scientific Pub. Ireland, Ltd., POB 85,
Limerick, Ireland) V.1- 1973- Volume(issue)/page/year: 77,81,1993
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Mammal - dog
DOSE/DURATION : 9 gm/kg/90D-C
TOXIC EFFECTS :
Liver - changes in liver weight
Biochemical - Enzyme inhibition, induction, or change in blood or tissue
levels - phosphatases
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E.
First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year:
54,514,1980
*** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***
NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
NOES - National Occupational Exposure Survey (1983)
NOES Hazard Code - X5417
No. of Facilities: 27695 (estimated)
No. of Industries: 202
No. of Occupations: 119
No. of Employees: 573193 (estimated)
No. of Female Employees: 38354 (estimated)
*** STATUS IN U.S. ***
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA Section 8(e) Risk Notification, 8EHQ-0892-9112;8EHQ-0892-9113
EPA TSCA Section 8(e) Risk Notification, 8EHQ-0892-9114
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998
*** END OF RECORD ***
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