*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : GO7300100
CHEMICAL NAME : o-Cresol,
4-((7-chloro-4-quinolyl)amino)-alpha-(diethylamino)-,
dihydrochloride
CAS REGISTRY NUMBER : 69-44-3
LAST UPDATED : 199707
DATA ITEMS CITED : 2
MOLECULAR FORMULA : C20-H22-Cl-N3-O.2Cl-H
MOLECULAR WEIGHT : 428.82
WISWESSER LINE NOTATION : T66 BNJ IG EMR DQ C1N2&2 &GH 2
COMPOUND DESCRIPTOR : Drug
Human
SYNONYMS/TRADE NAMES :
* Amodiaquin dihydrochloride
* Camoquin hydrochloride
* 4-((7-Chloro-4-quinolyl)amino)-alpha-(diethylamino)-o-cresol
dihydrochloride
* Phenol, 4-((7-chloro-4-quinolinyl)amino)-2-((diethylamino)methyl)-,
dihydrochloride
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Human - woman
DOSE/DURATION : 52 mg/kg/13W-I
TOXIC EFFECTS :
Blood - agranulocytosis
REFERENCE :
BMJOAE British Medical Journal. (British Medical Assoc., BMA House,
Tavistock Sq., London WC1H 9JR, UK) V.1- 1857- Volume(issue)/page/year:
292,717,1986
TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 137 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc.,
Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
20037) V.6- 1963- Volume(issue)/page/year: 24,1471,1981
*** END OF RECORD ***
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