2-Oxazolidinone,5-[(2-methoxyphenoxy)methyl]-

MSDS  :
 2-Oxazolidinone, 5-((o-methoxyphenoxy)methyl)-
CAS  
:
 70-07-5
SYNONYMS  
:
 * AHR 233
* Alkapol peg-400
* CL 27,319
* Control-OM
* Dorsiflex
* Dorsilon
* Ekilan
* Lenetran
* Lenetran TAB
* Lenetranat
* Mefenoxalona
* Mefenoxalone
* Mephenoxalone
* Methoxadone
* Methoxydon(E)
* 5-(o-Methoxyphenoxymethyl)-2-oxazolidinone
* 5-(o-Methoxyphenoxymethyl)-2-oxazolidone
* Metoxadone
* Moderamin
* OM 518
* Oxazolidinone
* Placidex
* Riself
* Transpoise
* Trepidone
* Valanas
* Xerene

Catalog of Chemical Suppliers, Buyers, Custom Synthesis Companies And Equipment Manufacturers
[ 2-Oxazolidinone, 5-((o-methoxyphenoxy)methyl)- 70-07-5 ]
                     *** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : RQ3500000
CHEMICAL NAME           : 2-Oxazolidinone, 5-((o-methoxyphenoxy)methyl)-
CAS REGISTRY NUMBER     : 70-07-5
BEILSTEIN REFERENCE NO. : 0530698
LAST UPDATED            : 199612
DATA ITEMS CITED        : 7
MOLECULAR FORMULA       : C11-H13-N-O4
MOLECULAR WEIGHT        : 223.25
WISWESSER LINE NOTATION : T5MVOTJ D1OR BO1
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * AHR 233
   * Alkapol peg-400
   * CL 27,319
   * Control-OM
   * Dorsiflex
   * Dorsilon
   * Ekilan
   * Lenetran
   * Lenetran TAB
   * Lenetranat
   * Mefenoxalona
   * Mefenoxalone
   * Mephenoxalone
   * Methoxadone
   * Methoxydon(E)
   * 5-(o-Methoxyphenoxymethyl)-2-oxazolidinone
   * 5-(o-Methoxyphenoxymethyl)-2-oxazolidone
   * Metoxadone
   * Moderamin
   * OM 518
   * Oxazolidinone
   * Placidex
   * Riself
   * Transpoise
   * Trepidone
   * Valanas
   * Xerene
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 3820 mg/kg
TOXIC EFFECTS :
   Sense Organs and Special Senses (Eye) - ptosis
   Behavioral - changes in motor activity (specific assay)
   Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   6,642,1964
 
TYPE OF TEST            : LD - Lethal dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >1 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 134,198,1961
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >5 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PSDTAP Proceedings of the European Society for the Study of Drug Toxicity.
   (Princeton, NJ 08540) V.1-15, 1963-74.  For publisher information, see
   PESTD5.  Volume(issue)/page/year: 11,212,1970
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 800 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   RAMAAB Revista de la Asociacion Medica Argentina.  (Buenos Aires, Argentina)
    V.1-89, 1915-76. Discontinued.  Volume(issue)/page/year: 74,82,1960
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 30330 mg/kg/30D-C
TOXIC EFFECTS :
   Nutritional and Gross Metabolic - weight loss or decreased weight gain
   Related to Chronic Data - changes in ovarian weight
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   4,220,1962
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : 18 gm/kg/30D-I
TOXIC EFFECTS :
   Behavioral - food intake (animal)
   Liver - other changes
   Blood - normocytic anemia
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   4,220,1962
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : 87 gm/kg/26W-I
TOXIC EFFECTS :
   Behavioral - ataxia
   Blood - normocytic anemia
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   4,220,1962
 
                            *** END OF RECORD ***
;

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