information Related products Suppliers

Acetic acid, 2-bromo-

1 - Product and Company Information

Product Name BROMOACETIC ACID, REAGENTPLUSTM, >=99%
Product Number 259357
2 - Composition/Information on Ingredients

Product Name CAS # EC no Annex I
Index Number
BROMOACETIC ACID 79-08-3 201-175-8 607-065-00-X

Formula C2H3BrO2
Molecular Weight 138.95 AMU
Synonyms Acide bromacetique (French) * Bromoacetate ion *
Bromoacetic acid * alpha-Bromoacetic acid *
Bromoethanoic acid * alpha-Bromoethanoic acid *
Kyselina bromoctova (Czech) *
Monobromessigsaeure (German) * Monobromoacetic
acid * To NTU

3 - Hazards Identification

SPECIAL INDICATION OF HAZARDS TO HUMANS AND THE ENVIRONMENT
Toxic by inhalation, in contact with skin and if swallowed. Causes
severe burns. Very toxic to aquatic organisms.

4 - First Aid Measures

AFTER INHALATION
If inhaled, remove to fresh air. If not breathing give
artificial respiration. If breathing is difficult, give oxygen.

AFTER SKIN CONTACT
In case of skin contact, flush with copious amounts of water for
at least 15 minutes. Remove contaminated clothing and shoes.
Call a physician.

AFTER EYE CONTACT
In case of contact with eyes, flush with copious amounts of
water for at least 15 minutes. Assure adequate flushing by
separating the eyelids with fingers. Call a physician.
AFTER INGESTION
If swallowed, wash out mouth with water provided person is
conscious. Call a physician immediately. Do not induce vomiting.

5 - Fire Fighting Measures

SPECIAL RISKS
Specific Hazard(s): Emits toxic fumes under fire conditions.

SPECIAL PROTECTIVE EQUIPMENT FOR FIREFIGHTERS
Wear self-contained breathing apparatus and protective clothing
to prevent contact with skin and eyes.

6 - Accidental Release Measures

PERSONAL PRECAUTION PROCEDURES TO BE FOLLOWED IN CASE OF LEAK OR SPILL
Evacuate area.

PROCEDURE(S) OF PERSONAL PRECAUTION(S)
Wear self-contained breathing apparatus, rubber boots, and heavy
rubber gloves.

METHODS FOR CLEANING UP
Sweep up, place in a bag and hold for waste disposal. Ventilate
area and wash spill site after material pickup is complete.

7 - Handling and Storage

HANDLING
Directions for Safe Handling: Do not breathe dust. Do not get in
eyes, on skin, on clothing. Avoid prolonged or repeated exposure.

STORAGE
Conditions of Storage: Keep tightly closed.

SPECIAL REQUIREMENTS: Light sensitive. Hygroscopic.

8 - Exposure Controls / Personal Protection

ENGINEERING CONTROLS
Safety shower and eye bath. Use only in a chemical fume hood.

GENERAL HYGIENE MEASURES
Wash contaminated clothing before reuse. Discard contaminated
shoes. Wash thoroughly after handling.

PERSONAL PROTECTIVE EQUIPMENT
Respiratory Protection: Government approved respirator.
Hand Protection: Compatible chemical-resistant gloves.
Eye Protection: Chemical safety goggles.

9 - Physical and Chemical Properties

Appearance Physical State: Solid
Color: Colorless
Form: Crystalline

Property Value At Temperature or Pressure

pH N/A
BP/BP Range 208 ?C 760 mmHg
MP/MP Range 46 ?C

Flash Point 113 ?C Method: closed cup
Flammability N/A
Autoignition Temp N/A
Oxidizing Properties N/A
Explosive Properties N/A
Explosion Limits N/A
Vapor Pressure 30 mmHg 127 ?C
SG/Density 1.934 g/cm3
Partition Coefficient Log Kow: 0.41
Viscosity N/A
Vapor Density N/A
Saturated Vapor Conc. N/A
Evaporation Rate N/A
Bulk Density N/A
Decomposition Temp. N/A
Solvent Content N/A
Water Content N/A
Surface Tension N/A
Conductivity N/A
Miscellaneous Data N/A
Solubility Solubility in Water:Soluble.

10 - Stability and Reactivity

STABILITY
Stable: Stable.
Conditions of Instability: May discolor on exposure to light.
Materials to Avoid: Strong oxidizing agents, Strong bases.

HAZARDOUS DECOMPOSITION PRODUCTS
Hazardous Decomposition Products: Carbon monoxide, Carbon dioxide,
Hydrogen bromide gas.

HAZARDOUS POLYMERIZATION
Hazardous Polymerization: Will not occur

11 - Toxicological Information

RTECS NUMBER: AF5950000

ACUTE TOXICITY

LD50
Oral
Rat
50 mg/kg
Remarks: Behavioral:Somnolence (general depressed activity).
Behavioral:Rigidity (includes catalepsy).

LD50
Skin
Rat
100 mg/kg

LD50
Intraperitoneal
Rat
50 MG/KG

LD50
Oral
Mouse

100 mg/kg

LD50
Intraperitoneal
Mouse
66 MG/KG
Remarks: Lungs, Thorax, or Respiration:Other changes.

LD50
Skin
Rabbit
59.9 mg/kg

SIGNS AND SYMPTOMS OF EXPOSURE
Inhalation may result in spasm, inflammation and edema of the
larynxand bronchi, chemical pneumonitis, and pulmonary edema.
Symptoms of exposure may include burning sensation, coughing,
wheezing, laryngitis, shortness of breath, headache, nausea, and
vomiting. Material is extremely destructive to tissue of the
mucous membranes and upper respiratory tract, eyes, and skin. To
the best of our knowledge, the chemical, physical, and
toxicological properties have not been thoroughly investigated.

ROUTE OF EXPOSURE
Skin Contact: Causes severe burns.
Skin Absorption: Toxic if absorbed through skin. Readily
absorbed through skin.
Eye Contact: Causes severe burns.
Inhalation: Material is extremely destructive to the tissue of
the mucous membranes and upper respiratory tract. Toxic if
inhaled.
Ingestion: Toxic if swallowed.

TARGET ORGAN INFORMATION
Kidneys. Liver.

CHRONIC EXPOSURE - MUTAGEN

Mouse
100 UMOL/L
Cell Type: leukocyte
DNA damage

12 - Ecological Information

ECOTOXICOLOGICAL EFFECTS

Test Type: EC50 Algae
Species: Scenedesmus subspicatus
Time: 72 h
Value: 0.02 - 14 mg/l

Test Type: EC50 Daphnia
Species: Daphnia magna
Time: 24 h
Value: 65 mg/l

13 - Disposal Considerations

SUBSTANCE DISPOSAL
Contact a licensed professional waste disposal service to dispose
of this material. Dissolve or mix the material with a combustible

solvent and burn in a chemical incinerator equipped with an
afterburner and scrubber. Observe all federal, state, and local
environmental regulations.

14 - Transport Information

RID/AD UN#: 3425
Class: 8
PG: II
Proper Shipping Name: Bromoacetic acid, solid

IMDG
UN#: 3425
Class: 8
PG: II
Proper Shipping Name: Bromoacetic acid, solid
Marine Pollutant: No
Severe Marine Pollutant: No

IATA
UN#: 3425
Class: 8
PG: II
Proper Shipping Name: Bromoacetic acid, solid
Inhalation Packing Group I: No

15 - Regulatory Information

CLASSIFICATION AND LABELING ACCORDING TO EU DIRECTIVES
ANNEX I INDEX NUMBER: 607-065-00-X
INDICATION OF DANGER: T C N
Toxic. Corrosive. Dangerous for the environment.
R-PHRASES: 23/24/25 35 50
Toxic by inhalation, in contact with skin and if swallowed.
Causes severe burns. Very toxic to aquatic organisms.
S-PHRASES: 26 36/37/39 45 61
In case of contact with eyes, rinse immediately with plenty of
water and seek medical advice. Wear suitable protective
clothing, gloves, and eye/face protection. In case of accident
or if you feel unwell, seek medical advice immediately (show
the label where possible). Avoid release to the environment.
Refer to special instructions/safety data sheets.

COUNTRY SPECIFIC INFORMATION

Germany
WGK: 2

SWITZERLAN SWISS POISON CLASS: 3

16 - Other Information

WARRANTY
The above information is believed to be correct but does not
purport to be all inclusive and shall be used only as a guide. The
information in this document is based on the present state of our
knowledge and is applicable to the product with regard to
appropriate safety precautions. It does not represent any
guarantee of the properties of the product. Sigma-Aldrich Inc.,
shall not be held liable for any damage resulting from handling or

from contact with the above product. See reverse side of invoice
or packing slip for additional terms and conditions of sale.
Copyright 2005 Sigma-Aldrich Co. License granted to make unlimited
paper copies for internal use only.

DISCLAIME For R&D use only. Not for drug, household or other uses.

;