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Benzenamine,N,N-dimethyl-4-[2-(4-quinolinyl)ethenyl]-

MSDS	:	Quinoline, 4-(p-(dimethylamino)styryl)-
CAS	:	897-55-2
SYNONYMS	:	* 2-(4-N,N-Dimethylaminostyryl)quinoline * 4-(p-(Dimethylamino)styryl)quinoline * 4-(4-Dimethylaminostyryl)quinoline * 4M20

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[ Quinoline, 4-(p-(dimethylamino)styryl)- 897-55-2 ]

                     *** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : VB7000000
CHEMICAL NAME           : Quinoline, 4-(p-(dimethylamino)styryl)-
CAS REGISTRY NUMBER     : 897-55-2
LAST UPDATED            : 199701
DATA ITEMS CITED        : 5
MOLECULAR FORMULA       : C19-H18-N2
MOLECULAR WEIGHT        : 274.39
WISWESSER LINE NOTATION : T66 BNJ E1U1R DN1&1
COMPOUND DESCRIPTOR     : Tumorigen
                          Drug
SYNONYMS/TRADE NAMES :
   * 2-(4-N,N-Dimethylaminostyryl)quinoline
   * 4-(p-(Dimethylamino)styryl)quinoline
   * 4-(4-Dimethylaminostyryl)quinoline
   * 4M20
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 160 mg/kg
TOXIC EFFECTS :
   Liver - fatty liver degeneration
   Liver - other changes
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   25,938,1965
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 100 mg/kg
TOXIC EFFECTS :
   Tumorigenic - neoplastic by RTECS criteria
   Liver - tumors
   Reproductive - Tumorigenic effects - ovarian tumors
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   25,938,1965

                              *** REVIEWS ***
 
   TOXICOLOGY REVIEW
   CRTXB2 CRC Critical Reviews in Toxicology.  (CRC Press, Inc., 2000 Corporate
   Blvd., NW, Boca Raton, FL 33431)  V.1-    1971- Volume(issue)/page/year:
   1(1),93,1971

   TOXICOLOGY REVIEW
   ADCSAJ Advances in Chemistry Series.  (American Chemical Soc., Distribution
   Office Dept. 223, POB 57136, West End Stn., Washington, DC 20037)  No.1-
   1950-  Volume(issue)/page/year: 13,271,1970

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY

 
                            *** END OF RECORD ***

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