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Phenothiazin-5-ium,3-amino-7-(dimethylamino)-2-methyl-, chloride (1:1)

1 - Product and Company Information

Product Name TOLUIDINE BLUE O
Product Number T3260
2 - Composition/Information on Ingredients

Product Name CAS # EC no Annex I
Index Number
TOLUIDINE BLUE O 92-31-9 202-146-2 None

Formula C15H16N3S.Cl
Molecular Weight 305.83 AMU
Synonyms Blutene chloride * C.I. Basic Blue 17 *
Dimethyltoluthionine chloride * F Klot * Gabilin
* Klot * Menodin * Modr Toluidinova (Czech) *
Modr Zasadita 17 (Czech) * Schultz 1041 *
Tolazul * Tolonium chloride * Toluidinblau
(German) * Toluidine Blue * Toluidine Blue O *
Toluidine Blue OO * Toluidine Blue
(phenothiazine dye)

3 - Hazards Identification

4 - First Aid Measures

AFTER INHALATION
If inhaled, remove to fresh air. If breathing becomes difficult,
call a physician.

AFTER SKIN CONTACT
In case of contact, immediately wash skin with soap and copious
amounts of water.

AFTER EYE CONTACT
In case of contact with eyes, flush with copious amounts of
water for at least 15 minutes. Assure adequate flushing by
separating the eyelids with fingers. Call a physician.

AFTER INGESTION
If swallowed, wash out mouth with water provided person is
conscious. Call a physician.
5 - Fire Fighting Measures

EXTINGUISHING MEDIA
Suitable: Water spray. Carbon dioxide, dry chemical powder, or
appropriate foam.

SPECIAL RISKS
Specific Hazard(s): Emits toxic fumes under fire conditions.

SPECIAL PROTECTIVE EQUIPMENT FOR FIREFIGHTERS
Wear self-contained breathing apparatus and protective clothing
to prevent contact with skin and eyes.

6 - Accidental Release Measures

PROCEDURE(S) OF PERSONAL PRECAUTION(S)
Exercise appropriate precautions to minimize direct contact with
skin or eyes and prevent inhalation of dust.

METHODS FOR CLEANING UP
Sweep up, place in a bag and hold for waste disposal. Avoid
raising dust. Ventilate area and wash spill site after material
pickup is complete.

7 - Handling and Storage

HANDLING
Directions for Safe Handling: Avoid inhalation. Avoid contact
with eyes, skin, and clothing. Avoid prolonged or repeated
exposure.

STORAGE
Conditions of Storage: Keep tightly closed.

8 - Exposure Controls / Personal Protection

ENGINEERING CONTROLS
Safety shower and eye bath. Mechanical exhaust required.

GENERAL HYGIENE MEASURES
Wash thoroughly after handling.

PERSONAL PROTECTIVE EQUIPMENT
Respiratory Protection: Wear dust mask.
Hand Protection: Protective gloves.
Eye Protection: Chemical safety goggles.

9 - Physical and Chemical Properties

Appearance Physical State: Solid
Color: Deep green
Form: Powder

Property Value At Temperature or Pressure

pH N/A
BP/BP Range N/A
MP/MP Range N/A
Flash Point N/A
Flammability N/A
Autoignition Temp N/A

SIGMA - T3260 www.-aldrich.com Oxidizing Properties N/A
Explosive Properties N/A
Explosion Limits N/A
Vapor Pressure N/A
SG/Density N/A
Partition Coefficient N/A
Viscosity N/A
Vapor Density N/A
Saturated Vapor Conc. N/A
Evaporation Rate N/A
Bulk Density N/A
Decomposition Temp. N/A
Solvent Content N/A
Water Content N/A
Surface Tension N/A
Conductivity N/A
Miscellaneous Data N/A
Solubility Other Solvents: METHANOL

10 - Stability and Reactivity

STABILITY
Stable: Stable.
Materials to Avoid: Strong oxidizing agents.

HAZARDOUS DECOMPOSITION PRODUCTS
Hazardous Decomposition Products: Carbon monoxide, Carbon dioxide,
Nitrogen oxides, Hydrogen chloride gas, Sulfur oxides.

HAZARDOUS POLYMERIZATION
Hazardous Polymerization: Will not occur

11 - Toxicological Information

RTECS NUMBER: SP5670000

ACUTE TOXICITY

LD50
Intraperitoneal
Rat
215 MG/KG

LD50
Intravenous
Rat
28930 UG/KG
Remarks: Behavioral:Convulsions or effect on seizure threshold.
Lungs, Thorax, or Respiration:Respiratory stimulation. Lungs,
Thorax, or Respiration:Other changes.

LD50
Intravenous
Mouse
27560 UG/KG
Remarks: Behavioral:Convulsions or effect on seizure threshold.
Lungs, Thorax, or Respiration:Respiratory stimulation. Lungs,
Thorax, or Respiration:Other changes.

LD50
Intravenous
Rabbit

SIGMA - T3260 www.-aldrich.com 13440 UG/KG
Remarks: Behavioral:Convulsions or effect on seizure threshold.
Lungs, Thorax, or Respiration:Respiratory stimulation. Lungs,
Thorax, or Respiration:Other changes.

SIGNS AND SYMPTOMS OF EXPOSURE
To the best of our knowledge, the chemical, physical, and
toxicological properties have not been thoroughly investigated.

ROUTE OF EXPOSURE
Skin Contact: May cause skin irritation.
Skin Absorption: May be harmful if absorbed through the skin.
Eye Contact: May cause eye irritation.
Inhalation: May be harmful if inhaled. Material may be
irritating to mucous membranes and upper respiratory tract.
Ingestion: May be harmful if swallowed.

CHRONIC EXPOSURE - MUTAGEN

Hamster
20 UMOL/L
5H
Cell Type: ovary
Cytogenetic analysis

12 - Ecological Information

No data available.

13 - Disposal Considerations

SUBSTANCE DISPOSAL
Contact a licensed professional waste disposal service to dispose
of this material. Dissolve or mix the material with a combustible
solvent and burn in a chemical incinerator equipped with an
afterburner and scrubber. Observe all federal, state, and local
environmental regulations.

14 - Transport Information

RID/AD Non-hazardous for road transport.

IMDG
Non-hazardous for sea transport.

IATA
Non-hazardous for air transport.

15 - Regulatory Information

CLASSIFICATION AND LABELING ACCORDING TO EU DIRECTIVES
S-PHRASES: 24/25 22
Avoid contact with skin and eyes. Do not breathe dust.

16 - Other Information

WARRANTY
The above information is believed to be correct but does not
purport to be all inclusive and shall be used only as a guide. The
information in this document is based on the present state of our
knowledge and is applicable to the product with regard to

SIGMA - T3260 www.-aldrich.com appropriate safety precautions. It does not represent any
guarantee of the properties of the product. Sigma-Aldrich Inc.,
shall not be held liable for any damage resulting from handling or
from contact with the above product. See reverse side of invoice
or packing slip for additional terms and conditions of sale.
Copyright 2005 Sigma-Aldrich Co. License granted to make unlimited
paper copies for internal use only.

DISCLAIME For R&D use only. Not for drug, household or other uses.

SIGMA - T3260 www.-aldrich.com
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