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Toxins, botulin, C

Material Safety Data Sheet
Customer
Order Number
Number
Section 1. Chemical Product and Company Identification
Common Name Botulinum Toxin C, Clostridium 203676
Catalog #
botulinum
Calbiochem-Novabiochem Corp.
Supplier In Case of Call Chemtrec?
10394 Pacific Center Court
Emergency (800)424-9300 (within U.S.A.)
San Diego, CA 92121
(703)527-3887 (outside U.S.A.)
(858)450-5558/(800)854-3417
FAX: (858)453-3552

Not available.
Synonym

Section 2. Composition, Information on Ingredients
CAS #
Name Exposure Limits

1) Botulinum Toxin C, Clostridium botulinum 93384-45-3 Not available.

Section 3. Hazards Identification
Liquid. (Supplied in 200mM NaCl and 50mM NaOAc, pH 6.0.)
Physical State and
Appearance
DANGER!
Emergency Overview
MAY BE FATAL IF INHALED, ABSORBED THROUGH SKIN OR SWALLOWED.
CAUSES DAMAGE TO THE FOLLOWING ORGANS: PERIPHERAL NERVOUS SYSTEM.
MAY CAUSE EYE AND SKIN IRRITATION.
MAY CAUSE DAMAGE TO THE FOLLOWING ORGANS: GASTROINTESTINAL TRACT, RESPIRATORY
TRACT, EYES, MUSCLE TISSUE.
Do not get in eyes, on skin or on clothing. Avoid contact with eyes, skin and clothing. Do not ingest.
Avoid breathing vapor or mist. Keep container closed. Use only with adequate ventilation. Wash
thoroughly after handling.
Absorbed through skin. Dermal contact. Eye contact. Inhalation. Ingestion.
Routes of Entry

Potential Acute Health Effects
Eyes Hazardous in case of eye contact (irritant).

Skin Extremely hazardous in case of skin contact (permeator). Hazardous in case of skin contact (irritant).
Severe over-exposure can result in death. Skin inflammation is characterized by itching, scaling,
reddening, or, occasionally, blistering.
Inhalation Extremely hazardous in case of inhalation. May be fatal if inhaled.

Ingestion Extremely hazardous in case of ingestion. May be fatal if swallowed.

CARCINOGENIC EFFECTS: Not available.
Potential Chronic Health
MUTAGENIC EFFECTSNot available.
:
Effects
TERATOGENIC EFFECTSNot available.
:
Repeated exposure to a highly toxic material may produce general deterioration of health by an
Medical Conditions
Aggravated by Overexposure: accumulation in one or many human organs.
Not available.
Overexposure
/Signs/Symptoms
See Toxicological Information (section 11)

203676 Catalog #
Section 4. First Aid Measures
Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water
Eye Contact
for at least 15 minutes. Get medical attention.
In case of contact, immediately flush skin with plenty of water for at least 15 minutes while removing
Skin Contact
contaminated clothing and shoes. Cover the irritated skin with an emollient. Wash clothing before reuse.
Thoroughly clean shoes before reuse. Get medical attention immediately.
If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give
Inhalation
oxygen. Get medical attention immediately.
If swallowed, do not induce vomiting unless directed to do so by medical personnel. Never give anything
Ingestion
by mouth to an unconscious person. Loosen tight clothing such as a collar, tie, belt or waistband. Get
medical attention immediately.
Notes to Physician Not available.

Section 5. Fire Fighting Measures
Flammability of the Product May be combustible at high temperature.

Not available.
Flash Points

Not available.
Products of Combustion

Not available.
Fire Hazards in Presence of
Various Substances

Risks of explosion of the product in presence of mechanical impact: Not available.
Explosion Hazards in
Risks of explosion of the product in presence of static discharge: Not available.
Presence of Various
Substances
Infectious material.
Fire Fighting Media
Use DRY chemical powder.
and Instructions

Be sure to use an approved/certified respirator or equivalent.
Protective Clothing (Fire)

Not available.
Special Remarks on Fire
Hazards
Not available.
Special Remarks on
Explosion Hazards

Section 6. Accidental Release Measures
Absorb with an inert material and put the spilled material in an appropriate waste disposal.
Small Spill and Leak

Infectious material. Poisonous liquid.
Large Spill and Leak
Stop leak if without risk. Do not touch damaged container or spilled material. Do not clean-up or dispose
except under supervision of a specialist. Cover damaged containers or spilled material with cloth wetted
with bleaching material (hypochlorite) or other disinfectant. Do not get water inside container. Do not
touch spilled material. Use water spray to reduce vapors. Prevent entry into sewers, basements or
confined areas; dike if needed. Eliminate all ignition sources. Call for assistance on disposal.

Section 7. Handling and Storage
Avoid contact with eyes, skin and clothing. Do not ingest. Avoid breathing vapors or spray mists. Keep
Handling
container closed. Use only with adequate ventilation. Wash thoroughly after handling.
Keep container tightly closed. Keep container in a cool, well-ventilated area. Do not store above -20??C
Storage
(-4??F).

203676 Catalog #
Section 8. Exposure Controls, Personal Protection
Provide exhaust ventilation or other engineering controls to keep the airborne concentrations of vapors
Engineering Controls
below their respective threshold limit value. Ensure that eyewash stations and safety showers are
proximal to the work-station location.
Personal Protection
Eyes Splash goggles.

Body Lab coat.

Respiratory Vapor respirator. Be sure to use an approved/certified respirator or equivalent. Wear appropriate
respirator when ventilation is inadequate.
Hands Gloves.

Feet Not applicable.

Protective Clothing
(Pictograms)

Splash goggles. Full suit. Vapor respirator. Boots. Gloves. A self-contained breathing apparatus should
Personal Protection in Case
be used to avoid inhalation of the product. Suggested protective clothing might not be sufficient; consult a
of a Large Spill
specialist BEFORE handling this product.
Exposure Limits
Product Name
Not available.
1) Botulinum Toxin C

Consult local authorities for acceptable exposure limits.

Section 9. Physical and Chemical Properties
Liquid. (Supplied in 200mM NaCl and 50mM
Physical State and Not available.
Color
NaOAc, pH 6.0.)
Appearance
500000 g/mole
Molecular Weight

Not available.
Molecular Formula

Not available.
Boiling/Condensation Point

Not available.
Melting/Freezing Point

Not available.
Specific Gravity

Not available.
Vapor Pressure

Not available.
Vapor Density

Not available.
Solubility

Section 10. Stability and Reactivity
The product is stable.
Stability and Reactivity

Incompatibility with Various Reactive with alkalis.
Substances
Not available.
Hazardous Decomposition
Products
Will not occur.
Hazardous Polymerization

203676 Catalog #
Section 11. Toxicological Information
RTECS # QQ4497200

LD50: Not available.
Toxicity to Animals
LC50: Not available.
Causes damage to the following organs: peripheral nervous system.
Chronic Effects on Humans
May cause damage to the following organs: gastrointestinal tract, upper respiratory tract, eyes, muscle
tissue.
Other Toxic Effects on Extremely hazardous in case of skin contact (permeator), of ingestion, of inhalation.
Humans Hazardous in case of skin contact (irritant).

Special Remarks on Toxicity Toxic for humans or animal life.
to Animals

Special Remarks on Chronic Not available.
Effects on Humans

Neurological hazard. Exposure can cause nausea, headache and vomiting. May be fatal.
Special Remarks on Other
Toxic Effects on Humans

Section 12. Ecological Information
Not available.
Ecotoxicity

Not available.
Toxicity of the Products of
Biodegradation

Section 13. Disposal Considerations
Waste must be disposed of in accordance with federal, state and local environmental control regulations.
Waste Information

Not available.
Waste Stream
Consult your local or regional authorities.

Section 14. Transport Information
Infectious substances, affecting humans
DOT Classification
INFECTIOUS INFECTIEUX
IN CASE OF DEMAGE EN CAS DE DOMMAGE
OR LEAKAGE OU DE FUITE COMMUNIQUE IMMEDIATLY NOTIFY IMMEDIATEMENT
LOCAL AVEC LES AUTORITES
AUTHORITIES LOCALES
OR OU
CANUTEC
613-996-9999

6

Infectious substances, affecting humans, 6.2, UN2814

CLASS 6.2: Infectious material.
TDG Classification
INFECTIOUS INFECTIEUX
IN CASE OF DEMAGE EN CAS DE DOMMAGE
OR LEAKAGE OU DE FUITE COMMUNIQUE IMMEDIATLY NOTIFY IMMEDIATEMENT
LOCAL AVEC LES AUTORITES
AUTHORITIES LOCALES
OR OU
CANUTEC
613-996-9999

6

Infectious substances, affecting humans, 6.2, UN2814

Not available.
Marine Pollutant

Not available.
Special Provisions for
Transport
CLASS 6.2: Infectious material.
ADR/RID Classification

CLASS 6.2: Infectious material.
IMO/IMDG Classification

CLASS 6.2: Infectious material.
ICAO/IATA Classification

203676 Catalog #
Section 15. Regulatory Information
CLASS: Highly toxic.
HCS Classification
CLASS: Irritating substance.
CLASS: Target organ effects.
TSCA: No products were found.
U.S. Federal Regulations
SARA 302/304/311/312 extremely hazardous substances: No products were found.
SARA 302/304 emergency planning and notification: No products were found.
SARA 302/304/311/312 hazardous chemicals: No products were found.
SARA 311/312 MSDS distribution - chemical inventory - hazard identification: No products were found.
SARA 313 toxic chemical notification and release reporting: No products were found.
Clean Water Act (CWA) 307: No products were found.
Clean Water Act (CWA) 311: No products were found.
Clean air act (CAA) 112 accidental release prevention: No products were found.
Clean air act (CAA) 112 regulated flammable substances: No products were found.
Clean air act (CAA) 112 regulated toxic substances: No products were found.
CLASS D-3: Infectious substance.
WHMIS (Canada)

No products were found.

International Regulations
Not available.
EINECS

R26/27/28- Very toxic by inhalation, in contact with skin and if swallowed.
DSCL (EEC)
R36/38- Irritating to eyes and skin.
No products were found.
International Lists

No products were found.
State Regulations
California prop. 65: No products were found.

Section 16. Other Information
MAY BE FATAL IF INHALED, ABSORBED THROUGH SKIN OR SWALLOWED.
Label Requirements
CAUSES DAMAGE TO THE FOLLOWING ORGANS: PERIPHERAL NERVOUS SYSTEM.
MAY CAUSE EYE AND SKIN IRRITATION.
MAY CAUSE DAMAGE TO THE FOLLOWING ORGANS: GASTROINTESTINAL TRACT,
RESPIRATORY TRACT, EYES, MUSCLE TISSUE.

Hazardous Material * 2 National Fire
Health
Fire Hazard
1
Information System 1 Protection
Fire Hazard
2 0
(U.S.A.) Association (U.S.A.) Health Reactivity
0
Reactivity
Specific Hazard
x
Personal Protection

Notice to Reader
To the best of our knowledge, the information contained herein is accurate. However, neither the above named supplier nor any of its subsidiaries
assumes any liability whatsoever for the accuracy or completeness of the information contained herein.
Final determination of suitability of any material is the sole responsibility of the user. All materials may present unknown hazards and should be used
with caution. Although certain hazards are described herein, we cannot guarantee that these are the only hazards that exist.

Date of issue
203676 Catalog # 4/10/2002.

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