6-Heptenoic acid,
7-(3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl
)- 3,5-dihydroxy-, (R*,S*-(E))-(+-)-

CAS  

 93957-54-1

SYNONYMS  

 * Fluvastatin

                     *** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : MJ9675050
CHEMICAL NAME           : 6-Heptenoic acid,
                          7-(3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl
                          )- 3,5-dihydroxy-, (R*,S*-(E))-(+-)-
CAS REGISTRY NUMBER     : 93957-54-1
LAST UPDATED            : 199712
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C24-H26-F-N-O4
MOLECULAR WEIGHT        : 411.51
SYNONYMS/TRADE NAMES :
   * Fluvastatin
 
                       *** HEALTH HAZARD DATA ***
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : 11648 mg/kg/2Y-I
TOXIC EFFECTS :
   Sense Organs and Special Senses (Eye) - effect, not otherwise specified
   Biochemical - Enzyme inhibition, induction, or change in blood or tissue
   levels - other Enzymes
REFERENCE :
   LETRET Lens and Eye Toxicity Research.  (Marcel Dekker, Journal Customer
   Service, POB 5017, Monticello, NY  12701)  V.6n.1-2-    1989-
   Volume(issue)/page/year: 7,563,1990
 
                            *** END OF RECORD ***