*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : DO7350000
CHEMICAL NAME : Benzyl alcohol,
p-hydroxy-alpha-((methylamino)methyl)-
CAS REGISTRY NUMBER : 94-07-5
LAST UPDATED : 199601
DATA ITEMS CITED : 5
MOLECULAR FORMULA : C9-H13-N-O2
MOLECULAR WEIGHT : 167.23
WISWESSER LINE NOTATION : QR DYQ1M1
COMPOUND DESCRIPTOR : Drug
SYNONYMS/TRADE NAMES :
* Analeptin
* Ethaphene
* 4-Hydroxy-alpha-((methylamino)methyl)benzenemethanol
* p-Hydroxy-alpha-((methylamino)methyl)benzyl alcohol
* p-Hydroxyphenylmethylaminoethanol
* 1-(4-Hydroxyphenyl)-2-methylaminoethanol
* 1-(4-Hydroxyphenyl)-N-methylethanolamine
* p-Methylaminoethanolphenol
* beta-Methylamino-alpha-(4-hydroxyphenyl)ethyl alcohol
* Methylaminomethyl(4-hydroxyphenyl)carbinol
* Oxedrine
* p-Oxedrine
* alpha-(4-Oxyphenyl)alpha-oxy-beta-methylaminoaethan
* Parakorper
* Parasympatol
* Pentedrin
* S 38537-9
* Simpalon
* Simpatol
* Sympathol
* Synefrin
* Synephrin
* Synephrine
* p-Synephrine
* Synthenate
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 1500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4-
1898- Volume(issue)/page/year: 101,81,1955
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams &
Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10-
Volume(issue)/page/year: 89,297,1947
TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 1500 mg/kg
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - effect, not otherwise specified
Behavioral - convulsions or effect on seizure threshold
Lungs, Thorax, or Respiration - respiratory stimulation
REFERENCE :
AEPPAE Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und
Pharmakologie. (Berlin, Ger.) V.110-253, 1925-66. For publisher
information, see NSAPCC. Volume(issue)/page/year: 136,172,1928
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 270 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams &
Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10-
Volume(issue)/page/year: 106,341,1952
TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 150 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4-
1898- Volume(issue)/page/year: 101,81,1955
*** END OF RECORD ***
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