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Phenol,2-amino-4,6-dinitro-

MSDS	:	Phenol, 2-amino-4,6-dinitro-
CAS	:	96-91-3
SYNONYMS	:	* Acide picramique * C.I. Oxidation Base 21 * 4,6-Dinitro-2-aminophenol * Fourrine 93 * Fourrine 4R * Furro 4R * Picramic acid * Zoba 4R

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[ Phenol, 2-amino-4,6-dinitro- 96-91-3 ]

                     *** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : SJ5800000
CHEMICAL NAME           : Phenol, 2-amino-4,6-dinitro-
CAS REGISTRY NUMBER     : 96-91-3
BEILSTEIN REFERENCE NO. : 0989416
REFERENCE               : 4-13-00-00909 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 5
MOLECULAR FORMULA       : C6-H5-N3-O5
MOLECULAR WEIGHT        : 199.14
WISWESSER LINE NOTATION : WNR CZ DQ ENW
COMPOUND DESCRIPTOR     : Mutagen
SYNONYMS/TRADE NAMES :
   * Acide picramique
   * C.I. Oxidation Base 21
   * 4,6-Dinitro-2-aminophenol
   * Fourrine 93
   * Fourrine 4R
   * Furro 4R
   * Picramic acid
   * Zoba 4R
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 2100 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 53,58,1935
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : 150 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Cardiac - other changes
   Gastrointestinal - hypermotility, diarrhea
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 50,20,1935
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Bird - pigeon
DOSE/DURATION           : 140 mg/kg
TOXIC EFFECTS :
   Behavioral - altered sleep time (including change in righting reflex)
   Behavioral - rigidity (including catalepsy)
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 50,20,1935
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intramuscular
SPECIES OBSERVED        : Bird - pigeon
DOSE/DURATION           : 100 mg/kg
TOXIC EFFECTS :
   Nutritional and Gross Metabolic - body temperature increase
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 53,58,1935
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 5 umol/plate
REFERENCE :
   NEZAAQ Nippon Eiseigaku Zasshi.  Japanese Journal of Hygiene.  (Nippon Eisei
   Gakkai, c/o Kyoto Daigaku Igakubu, Konoe-cho, Yoshida, Sakyo-ku, Kyoto 606,
   Japan)  V.1-    1946-  Volume(issue)/page/year: 38,533,1983
 
                            *** END OF RECORD ***

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