*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : SN0525000
CHEMICAL NAME : Phenol, 2,2'-thiobis(4,6-dichloro-
CAS REGISTRY NUMBER : 97-18-7
BEILSTEIN REFERENCE NO. : 2003535
REFERENCE : 4-06-00-05646 (Beilstein Handbook Reference)
LAST UPDATED : 199710
DATA ITEMS CITED : 8
MOLECULAR FORMULA : C12-H6-Cl4-O2-S
MOLECULAR WEIGHT : 356.04
WISWESSER LINE NOTATION : QR BG DG FSR BQ CG EG
COMPOUND DESCRIPTOR : Agricultural Chemical
Tumorigen
Drug
SYNONYMS/TRADE NAMES :
* Actamer
* Bidiphen
* Bis(3,5-dichloro-2-hydroxyphenyl) sulfide
* Bis(2-hydroxy-3,5-dichlorophenyl) sulfide
* Bithionol
* Bitin
* Bitionol
* CP 3438
* D 26
* 2,2'-Dihydroxy-3,3',5,5'-tetrachlorodiphenylsulfide
* 2-Hydroxy-3,5-dichlorophenyl sulphide
* Lorothidol
* Lorothiodol
* NCI-C60628
* Neopellis
* Nobacter
* 2,2'-Thiobis(4,6-dichlorophenol)
* TKhsd
* USAF B-22
* Vancide BL
* XL 7
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 7 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CLDND* Compilation of LD50 Values of New Drugs. (J.R. MacDougal, Dept. of
National Health and Welfare, Food and Drug Divisions, 35 John St., Ottawa,
Ont., Canada)
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 760 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo,
Japan) Volume(issue)/page/year: 6,612,1982
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 100 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161)
Formerly U.S. Clearinghouse for Scientific & Technical Information.
Volume(issue)/page/year: AD277-689
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 18 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems
Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010)
Volume(issue)/page/year: NX#01763
** TUMORIGENIC DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 12 gm/kg/78W-I
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria
Lungs, Thorax, or Respiration - tumors
Blood - tumors
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161)
Formerly U.S. Clearinghouse for Scientific & Technical Information.
Volume(issue)/page/year: PB223-159
*** STATUS IN U.S. ***
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998
*** END OF RECORD ***
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