*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : NX5014000
CHEMICAL NAME : Isoquinoline,
1,2,3,4-tetrahydro-6,7-diethoxy-1-((3,4-diethoxypheny
l)methylene)-, hydrochloride
CAS REGISTRY NUMBER : 985-12-6
LAST UPDATED : 199606
DATA ITEMS CITED : 4
MOLECULAR FORMULA : C24-H31-N-O4.Cl-H
MOLECULAR WEIGHT : 434.02
COMPOUND DESCRIPTOR : Drug
SYNONYMS/TRADE NAMES :
* Drotaverine hydrochloride
* Drotaverin hydrochloride
* Drotaverinium chloride
* Isodihydroperparine hydrochloride
* Isoquinoline,
1-(3,4-diethoxybenzylidene)-6,7-diethoxy-1,2,3,4-tetrahydro-,
hydrochloride
* No-Spa
* No-Spa hydrochloride
* 6,7,3',4'-Tetraethoxy-1-benzal-1,2,3,4-tetrahydroisoquinoline
hydrochloride
* Tetraspasmin-Lefa
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 540 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
USXXAM United States Patent Document. (U.S. Patent Office, Box 9,
Washington, DC 20231) Volume(issue)/page/year: #4035366
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 14600 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
USXXAM United States Patent Document. (U.S. Patent Office, Box 9,
Washington, DC 20231) Volume(issue)/page/year: #4035366
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 350 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
USXXAM United States Patent Document. (U.S. Patent Office, Box 9,
Washington, DC 20231) Volume(issue)/page/year: #4035366
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 15 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
USXXAM United States Patent Document. (U.S. Patent Office, Box 9,
Washington, DC 20231) Volume(issue)/page/year: #4035366
*** END OF RECORD ***
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