information Related products Suppliers

Benzenesulfonylchloride, 4-methyl-

1 - Product and Company Information

Product Name P-TOLUENESULFONYL CHLORIDE,
REAGENTPLUSTM, >=99%
Product Number 240877
2 - Composition/Information on Ingredients

Product Name CAS # EC no Annex I
Index Number
P-TOLUENESULFONYL CHLORIDE 98-59-9 202-684-8 None

Formula C7H7ClO2S
Molecular Weight 190.65 AMU
Synonyms TOSYL CHLORIDE

3 - Hazards Identification

SPECIAL INDICATION OF HAZARDS TO HUMANS AND THE ENVIRONMENT
Causes burns.

4 - First Aid Measures

AFTER INHALATION
If inhaled, remove to fresh air. If not breathing give
artificial respiration. If breathing is difficult, give oxygen.

AFTER SKIN CONTACT
In case of skin contact, flush with copious amounts of water for
at least 15 minutes. Remove contaminated clothing and shoes.
Call a physician.

AFTER EYE CONTACT
In case of contact with eyes, flush with copious amounts of
water for at least 15 minutes. Assure adequate flushing by
separating the eyelids with fingers. Call a physician.

AFTER INGESTION
If swallowed, wash out mouth with water provided person is
conscious. Call a physician immediately. Do not induce vomiting.
5 - Fire Fighting Measures

CONDITIONS OF FLAMMABILITY
Water hydrolyzes material liberating acidic gas which in contact
with metal surfaces can generate flammable and/or explosive
hydrogen gas.

EXTINGUISHING MEDIA
Suitable: Carbon dioxide, dry chemical powder, or appropriate
foam.
Unsuitable: Do not use water.

SPECIAL RISKS
Specific Hazard(s): Emits toxic fumes under fire conditions.

SPECIAL PROTECTIVE EQUIPMENT FOR FIREFIGHTERS
Wear self-contained breathing apparatus and protective clothing
to prevent contact with skin and eyes.

6 - Accidental Release Measures

PERSONAL PRECAUTION PROCEDURES TO BE FOLLOWED IN CASE OF LEAK OR SPILL
Evacuate area.

PROCEDURE(S) OF PERSONAL PRECAUTION(S)
Wear self-contained breathing apparatus, rubber boots, and heavy
rubber gloves.

METHODS FOR CLEANING UP
Sweep up, place in a bag and hold for waste disposal. Ventilate
area and wash spill site after material pickup is complete.

7 - Handling and Storage

HANDLING
Directions for Safe Handling: Do not breathe dust. Do not get in
eyes, on skin, on clothing. Avoid prolonged or repeated exposure.

STORAGE
Conditions of Storage: Store under inert gas. Keep tightly
closed. Store in a cool dry place.

SPECIAL REQUIREMENTS: Store under inert gas. Moisture sensitive.

8 - Exposure Controls / Personal Protection

ENGINEERING CONTROLS
Safety shower and eye bath. Use only in a chemical fume hood.

GENERAL HYGIENE MEASURES
Wash contaminated clothing before reuse. Discard contaminated
shoes. Wash thoroughly after handling.

EXPOSURE LIMITS - UNITED KINGDOM
Source Type Value
OEL STEL 5 mg/m3

PERSONAL PROTECTIVE EQUIPMENT
Respiratory Protection: Government approved respirator.
Hand Protection: Compatible chemical-resistant gloves.
Eye Protection: Chemical safety goggles.

9 - Physical and Chemical Properties

Appearance Physical State: Solid
Color: Colorless
Form: Crystals

Property Value At Temperature or Pressure

pH N/A
BP/BP Range 134 ??C 10 mmHg
MP/MP Range 66 ??C
Flash Point N/A
Flammability N/A
Autoignition Temp N/A
Oxidizing Properties N/A
Explosive Properties N/A
Explosion Limits N/A
Vapor Pressure 1 mmHg 88 ??C
SG/Density N/A
Partition Coefficient N/A
Viscosity N/A
Vapor Density N/A
Saturated Vapor Conc. N/A
Evaporation Rate N/A
Bulk Density N/A
Decomposition Temp. N/A
Solvent Content N/A
Water Content N/A
Surface Tension N/A
Conductivity N/A
Miscellaneous Data N/A
Solubility Solubility in Water:Insoluble.
Solvent: 0.2 g/ml CH2Cl2 Clear

10 - Stability and Reactivity

STABILITY
Stable: Stable.
Conditions to Avoid: Moisture.
Materials to Avoid: Strong oxidizing agents, Strong bases.

HAZARDOUS DECOMPOSITION PRODUCTS
Hazardous Decomposition Products: Carbon monoxide, Carbon dioxide,
Sulfur oxides, Hydrogen chloride gas.

HAZARDOUS POLYMERIZATION
Hazardous Polymerization: Will not occur

11 - Toxicological Information

ACUTE TOXICITY
LD50
Oral
Rat
4,680 mg/kg

IRRITATION DATA
Skin
Remarks: Severe irritation effect
Eyes
Remarks: Severe irritation effect

SIGNS AND SYMPTOMS OF EXPOSURE
Inhalation may result in spasm, inflammation and edema of the
larynxand bronchi, chemical pneumonitis, and pulmonary edema.
Symptoms of exposure may include burning sensation, coughing,
wheezing, laryngitis, shortness of breath, headache, nausea, and
vomiting. Material is extremely destructive to tissue of the
mucous membranes and upper respiratory tract, eyes, and skin. To
the best of our knowledge, the chemical, physical, and
toxicological properties have not been thoroughly investigated.

ROUTE OF EXPOSURE
Skin Contact: Causes burns. Causes blisters on contact with skin.
Skin Absorption: May be harmful if absorbed through the skin.
Eye Contact: Causes burns. Lachrymator.
Inhalation: Material is extremely destructive to the tissue of
the mucous membranes and upper respiratory tract. May be harmful
if inhaled.
Ingestion: May be harmful if swallowed.

12 - Ecological Information

ECOTOXICOLOGICAL EFFECTS

Test Type: LC50 Fish
Species: Brachydanio rerio
Time: 96 h
Value: > 100 mg/l

13 - Disposal Considerations

SUBSTANCE DISPOSAL
Contact a licensed professional waste disposal service to dispose
of this material. Dissolve or mix the material with a combustible
solvent and burn in a chemical incinerator equipped with an
afterburner and scrubber. Observe all federal, state, and local
environmental regulations.

14 - Transport Information

RID/AD UN#: 3261
Class: 8
PG: II
Proper Shipping Name: Corrosive solid, acidic,
organic, n.o.s.

IMDG
UN#: 3261
Class: 8
PG: II
Proper Shipping Name: CORROSIVE SOLID, ACIDIC,
ORGANIC, N.O.S.
Marine Pollutant: No
Severe Marine Pollutant: No
Technical Name: Required

IATA
UN#: 3261
Class: 8
PG: II
Proper Shipping Name: Corrosive solid, acidic,
organic, n.o.s.

Inhalation Packing Group I: No
Technical Name: Required

15 - Regulatory Information

CLASSIFICATION AND LABELING ACCORDING TO EU DIRECTIVES
INDICATION OF DANGER: C
Corrosive.
R-PHRASES: 34
Causes burns.
S-PHRASES: 26 36/37/39 45
In case of contact with eyes, rinse immediately with plenty of
water and seek medical advice. Wear suitable protective
clothing, gloves, and eye/face protection. In case of accident
or if you feel unwell, seek medical advice immediately (show
the label where possible).

SWITZERLAN SWISS POISON CLASS: 2

16 - Other Information

WARRANTY
The above information is believed to be correct but does not
purport to be all inclusive and shall be used only as a guide. The
information in this document is based on the present state of our
knowledge and is applicable to the product with regard to
appropriate safety precautions. It does not represent any
guarantee of the properties of the product. Sigma-Aldrich Inc.,
shall not be held liable for any damage resulting from handling or
from contact with the above product. See reverse side of invoice
or packing slip for additional terms and conditions of sale.
Copyright 2005 Sigma-Aldrich Co. License granted to make unlimited
paper copies for internal use only.

DISCLAIME For R&D use only. Not for drug, household or other uses.

;