*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : AM8050000
CHEMICAL NAME : Acetophenone, 3',4'-dihydroxy-2-(methylamino)-
CAS REGISTRY NUMBER : 99-45-6
BEILSTEIN REFERENCE NO. : 2366101
REFERENCE : 4-14-00-00832 (Beilstein Handbook Reference)
LAST UPDATED : 199612
DATA ITEMS CITED : 4
MOLECULAR FORMULA : C9-H11-N-O3
MOLECULAR WEIGHT : 181.21
WISWESSER LINE NOTATION : QR BQ DV1M1
COMPOUND DESCRIPTOR : Drug
Mutagen
SYNONYMS/TRADE NAMES :
* Adrenalone
* Adrenon
* Adrenone
* Chemosan
* 3,4-Dihydroxy-alpha-methylaminoacetophenone
* 3',4'-Dihydroxy-2-(methylamino)acetophenone
* 1-(3,4-Dihydroxyphenyl)-2-(methylamino)ethanone
* Ethanone, 1-(3,4-dihydroxyphenyl)-2-(methylamino)-
* Haemodan
* Kephrine
* Ketogaze
* Methaminoacetocatechol
* 4-Methylaminoacetocatechol
* 4-Methylaminoacetopyrocatechol
* Remestyp
* Stryphnon
* Stryphnone
* Styphnone
* Stypnon
* U 2134
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 275 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AEPPAE Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und
Pharmakologie. (Berlin, Ger.) V.110-253, 1925-66. For publisher
information, see NSAPCC. Volume(issue)/page/year: 226,493,1955
TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Unreported
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 2 gm/kg
TOXIC EFFECTS :
Autonomic Nervous System - sympathomimetic
REFERENCE :
AEPPAE Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und
Pharmakologie. (Berlin, Ger.) V.110-253, 1925-66. For publisher
information, see NSAPCC. Volume(issue)/page/year: 153,161,1930
** MUTATION DATA **
TYPE OF TEST : DNA damage
TEST SYSTEM : Microorganism - not otherwise specified
DOSE/DURATION : 250 umol/L
REFERENCE :
ABCHA6 Agricultural and Biological Chemistry. (Maruzen Co. Ltd., POB 5050,
Tokyo International, Tokyo 100-31, Japan) V.25- 1961-
Volume(issue)/page/year: 42,1019,1978
TYPE OF TEST : DNA damage
TEST SYSTEM : Rodent - rat Lung
DOSE/DURATION : 250 umol/L
REFERENCE :
ABCHA6 Agricultural and Biological Chemistry. (Maruzen Co. Ltd., POB 5050,
Tokyo International, Tokyo 100-31, Japan) V.25- 1961-
Volume(issue)/page/year: 42,1019,1978
*** END OF RECORD ***
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