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7,9,11,13-Eicosatetraenoicacid, 5,6,15-trihydroxy-, (5S,6R,7E,9E,11Z,13E,15S)-

Conforms to 93/112/EC and ISO 11014-1

SAFETY DATA SHEET
Order Customer
Number
Number

Identification of the substance/preparation and of the company/undertaking
1.
Lipoxin A : 437720
Product name : Catalog #
4

: Manufactured by EMD Biosciences, Inc.
Supplier
10394 Pacific Center Court
Chemical formula C20H32O5
:
San Diego, CA 92121
(858)450-5558/(800)854-3417
FAX: (858)453-3552

5(S),6(R),15(S)-Trihydroxyeicosa-7-trans-9-trans-11-cis-13-tran
:
Synonym
Acid; LXA

Emergency : Call Chemtrec?
telephone number (800)424-9300 (within U.S.A.)
(703)527-3887 (outside U.S.A.)

Composition / information on ingredients
2.
: Substance
Substance/Preparation

Chemical name* CAS No. EC Number Symbol R-Phrases
1) 89663-86-5 Not available. F, Xi R11, R36/37/38
5(S),6(R),15(S)-Trihydroxyeicosa-7-trans-9-trans-11-cis-13-
Acid; LXA

Hazards identification
3.
: Highly flammable.
Physical/chemical hazards
: WARNING!
Human health hazards
HIGHLY FLAMMABLE LIQUID AND VAPOR.
VAPOR MAY CAUSE FLASH FIRE.
MAY CAUSE RESPIRATORY TRACT, EYE AND SKIN IRRITATION.

First-aid measures
4.
First-Aid measures
: If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
Inhalation
Get medical attention.
: Do NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an
Ingestion
unconscious person. Loosen tight clothing such as a collar, tie, belt or waistband. Get medical attention if
symptoms appear.
: In case of contact, immediately flush skin with plenty of water. Cover the irritated skin with an emollient.
Skin Contact
Remove contaminated clothing and shoes. Wash clothing before reuse. Thoroughly clean shoes before reuse.
Get medical attention.
: Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at
Eye Contact
least 15 minutes. Get medical attention.

Effects and symptoms
Inhalation : Hazardous in case of inhalation (lung irritant).
: Hazardous in case of skin contact (irritant). Skin inflammation is characterized by itching, scaling, reddening,
Skin Contact
or, occasionally, blistering.
: Hazardous in case of eye contact (irritant).
Eye Contact
: Repeated or prolonged exposure is not known to aggravate medical condition.
Aggravating conditions

437720
Catalog #
5. Fire-fighting measures
: Flammable.
Flammability of the Product
Extinguishing Media
: Flammable liquid.
Suitable
SMALL FIRE: Use DRY chemical powder.
LARGE FIRE: Use alcohol foam, water spray or fog.
Hazardous thermal (de)composition : These products are carbon oxides (CO, CO2).
products
: Fire fighters should wear positive pressure self-contained breathing apparatus (SCBA) and full turnout gear.
Special fire-fighting procedures
: Be sure to use an approved/certified respirator or equivalent.
Protection of fire-fighters

Accidental release measures
6.
: Splash goggles. Full suit. Vapor respirator. Boots. Gloves. A self-contained breathing apparatus should be
Personal precautions
used to avoid inhalation of the product. Suggested protective clothing might not be sufficient; consult a
specialist BEFORE handling this product.
: Absorb with an inert material and put the spilled material in an appropriate waste disposa
Small Spill and Leak

: Flammable liquid.
Large Spill and Leak
Keep away from heat. Keep away from sources of ignition. Stop leak if without risk. Absorb with DRY
earth, sand or other non-combustible material. Do not touch spilled material. Prevent entry into sewers,
basements or confined areas; dike if needed.

Handling and storage
7.
: Keep away from heat. Keep away from sources of ignition. Ground all equipment containing material. Do not
Handling
ingest. Do not breathe gas/fumes/ vapor/spray. Wear suitable protective clothing. If ingested, seek medical
advice immediately and show the container or the label. Avoid contact with skin and eyes.
: Store in a segregated and approved area. Keep container in a cool, well-ventilated area. Keep container
Storage
tightly closed and sealed until ready for use. Avoid all possible sources of ignition (spark or flame). Do not
store above -70??C (-94??F).
Packaging materials
: Use original container.
Recommended use

Exposure controls/personal protection
8.
: Provide exhaust ventilation or other engineering controls to keep the airborne concentrations of vapors below
Engineering measures
their respective threshold limit value. Ensure that eyewash stations and safety showers are proximal to the
work-station location.
: Wash hands after handling compounds and before eating, smoking, using lavatory, and at the end of day.
Hygiene measures
Ingredient Name Occupational Exposure Limits
1) Lipoxin A4 Not available.

Personal protective equipment
: Vapor respirator. Be sure to use an approved/certified respirator or equivalent. Wear appropriate respirator
Respiratory system
when ventilation is inadequate.
: Lab coat.
Skin and body
: Gloves.
Hands
: Splash goggles.
Eyes
:
Protective Clothing
(Pictograms)

Physical and chemical properties
9.
: Liquid. (Thick oily liquid. Supplied in ethanol.)
Physical state
Color : Not available.
: 352.5 g/mole
Molecular Weight
: Not available.
Solubility
Flash point : Not available.
: Risks of explosion of the product in presence of mechanical impact: Not available.
Explosive properties
Risks of explosion of the product in presence of static discharge: Not available.

437720
Catalog #
10. Stability and reactivity
: The product is stable.
Stability
: Not available.
Conditions to avoid
: These products are carbon oxides (CO, CO2).
Hazardous Decomposition Products

11. Toxicological information
:
RTECS # KQ6300000 (Ethanol)
Local effects
Skin irritation : Hazardous in case of skin contact (irritant).
: Acute oral toxicity (LD50): 7060 mg/kg [Rat].
Acute toxicity
: Repeated or prolonged exposure is not known to aggravate medical condition.
Chronic toxicity
: Not available.
Other Toxic Effects on
Humans Hazardous in case of skin contact (irritant), of inhalation (lung irritant).

Not available.

Material is irritating to mucous membranes and upper respiratory tract. To the best of our knowledge, the
toxicological properties of this product have not been thoroughly investigated.

Carcinogenic effects : Not available.
: Not available.
Mutagenic effects
Reproduction toxicity : Not available.
: Not available.
Teratogenic effects

12. Ecological information
: Not available.
Ecotoxicity
: The product itself and its products of degradation are not toxic.
Toxicity of the Products of
Biodegradation

13. Disposal considerations
: Waste must be disposed of in accordance with federal, state and local environmental control regulations.
Methods of disposal; Waste of
residues; Contaminated packaging

14. Transport information
International transport regulations
: UN1170
UN number
Land - Road/Railway
: Ethanol solution
Proper shipping name
: CLASS 3: Flammable liquid A.
ADR/RID Class
: II
Packing Group
ADR/RID label :

Sea
: Ethanol solution
Proper shipping name
: CLASS 3.1: Flammable liquid (Low flashpoint group of liquids having a flashpoint below -18??C (0??F) c.c.).
IMDG Class
: II
Packing Group
IMDG label :

3

Air
: Ethanol solution
Proper shipping name
: UN1170
UN/ID Number

437720
Catalog #
: CLASS 3: Flammable liquid.
IATA-DGR Class
IATA label :

3

: Not available.
Special Provisions for
Transport

15. Regulatory information
EU Regulations
Hazard symbol(s) :

: Highly flammable, Irritant
Classification
: R11- Highly flammable.
Risk Phrases
R36/37/38- Irritating to eyes, respiratory system and skin.
: S7- Keep container tightly closed.
Safety Phrases
S16- Keep away from sources of ignition - No smoking.
S26- In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36- Wear suitable protective clothing.
: TSCA: No products were found.
U.S. Federal Regulations
SARA 302/304/311/312 extremely hazardous substances: No products were found.
SARA 302/304 emergency planning and notification: No products were found.
SARA 302/304/311/312 hazardous chemicals: No products were found.
SARA 311/312 MSDS distribution - chemical inventory - hazard identification: No products were found.
SARA 313 toxic chemical notification and release reporting: No products were found.
Clean Water Act (CWA) 307: No products were found.
Clean Water Act (CWA) 311: No products were found.
Clean air act (CAA) 112 accidental release prevention: No products were found.
Clean air act (CAA) 112 regulated flammable substances: No products were found.
Clean air act (CAA) 112 regulated toxic substances: No products were found.
: CLASS: Flammable liquid having a flash point lower than 37.8??C (100??F).
HCS Classification
CLASS: Irritating substance.
CLASS: Target organ effects.
:
State Regulations

: CLASS B-2: Flammable liquid with a flash point lower than 37.8??C (100??F).
WHMIS (Canada)
No products were found.

16. Other information
Hazardous Material 2 National Fire
Health
Fire Hazard
1
Information System 1 Protection
Fire Hazard
(U.S.A.) Association (U.S.A.) 2 0
Health Reactivity
0
Reactivity
Specific Hazard
h
Personal Protection

Notice to Reader
To the best of our knowledge, the information contained herein is accurate. However, neither the above named supplier nor any of its
subsidiaries assumes any liability whatsoever for the accuracy or completeness of the information contained herein.
Final determination of suitability of any material is the sole responsibility of the user. All materials may present unknown hazards and should be
used with caution. Although certain hazards are described herein, we cannot guarantee that these are the only hazards that exist.
Date of issue
3/6/2003.
437720
Catalog #

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