*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : DU3103500
CHEMICAL NAME : (2,2'-Binaphthalene)-8,8'-dicarboxaldehyde,
1,1',6,6',7,7'-hexahydroxy-3,3'-dimethyl-
5,5'-bis(1-methylethyl)-, (-)-
CAS REGISTRY NUMBER : 90141-22-3
BEILSTEIN REFERENCE NO. : 1917878
REFERENCE : 4-08-00-03754 (Beilstein Handbook Reference)
LAST UPDATED : 199612
DATA ITEMS CITED : 2
MOLECULAR FORMULA : C30-H30-O8
MOLECULAR WEIGHT : 518.60
COMPOUND DESCRIPTOR : Reproductive Effector
SYNONYMS/TRADE NAMES :
* (-)-Gossypol
*** HEALTH HAZARD DATA ***
** REPRODUCTIVE DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE : 210 mg/kg
SEX/DURATION : male 2 week(s) pre-mating
TOXIC EFFECTS :
Reproductive - Paternal Effects - spermatogenesis (incl. genetic material,
sperm morphology, motility, and count)
Reproductive - Fertility - male fertility index (e.g. # males impregnating
females per # males exposed to fertile nonpregnant females)
REFERENCE :
JOETD7 Journal of Ethnopharmacology. (Elsevier Scientific Pub. Ireland
Ltd., POB 85, Limerick, Ireland) V.1- 1979- Volume(issue)/page/year:
20,21,1987
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - hamster
DOSE : 320 mg/kg
SEX/DURATION : male 40 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Fertility - male fertility index (e.g. # males impregnating
females per # males exposed to fertile nonpregnant females)
REFERENCE :
CCPTAY Contraception. (Geron-X, Inc., POB 1108, Los Altos, CA 94022) V.1-
1970- Volume(issue)/page/year: 31,141,1985
*** END OF RECORD ***
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